LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 72
hr
 1311 3702 4935 0.7501 0.7205
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 72
hr
 1311 3377 4935 0.6842 0.6395
MDA-MB-231 Pictilisib
10
uM
LJP6
 72
hr
 1311 2597 4935 0.5263 0.4295
MDA-MB-231 PD184352
0.04
uM
LJP5
 72
hr
 1311 5023 5079 0.9891 0.9889
MDA-MB-231 PD184352
0.12
uM
LJP5
 72
hr
 1311 4341 5079 0.8547 0.8453
MDA-MB-231 PD184352
0.37
uM
LJP5
 72
hr
 1311 4016 5079 0.7908 0.7734
MDA-MB-231 PD184352
1.11
uM
LJP5
 72
hr
 1311 3403 5079 0.6701 0.6292
MDA-MB-231 PD184352
3.33
uM
LJP5
 72
hr
 1311 2896 5079 0.5704 0.5003
MDA-MB-231 PD184352
10
uM
LJP5
 72
hr
 1311 1877 5079 0.3697 0.2016
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 72
hr
 1311 5160 5079 1.0161 1.0162
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 72
hr
 1311 5140 5079 1.0119 1.0120
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 72
hr
 1311 5164 5079 1.0168 1.0168
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 72
hr
 1311 4897 5079 0.9641 0.9628
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 72
hr
 1311 4469 5079 0.8795 0.8717
MDA-MB-231 PLX-4720
10
uM
LJP5
 72
hr
 1311 3679 5079 0.7239 0.6926
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 72
hr
 1311 4495 4935 0.9111 0.9049
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 72
hr
 1311 4692 4935 0.9506 0.9472
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 72
hr
 1311 4748 4935 0.9619 0.9596
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 72
hr
 1311 4650 4935 0.9421 0.9385
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 72
hr
 1311 4638 4935 0.9397 0.9358
MDA-MB-231 Lapatinib
10
uM
LJP6
 72
hr
 1311 3377 4935 0.6844 0.6398
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 72
hr
 1311 4261 4935 0.8639 0.8518
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 72
hr
 1311 4149 4935 0.8410 0.8265
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 72
hr
 1311 4250 4935 0.8614 0.8492
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 72
hr
 1311 4180 4935 0.8472 0.8335