LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 GSK1059615
0.04
uM
LJP5
 72
hr
 1389 6304 5905 1.0686 1.0648
MCF7 GSK1059615
0.04
uM
LJP6
 72
hr
 1389 5101 5445 0.9340 0.9285
MCF7 GSK1059615
0.12
uM
LJP5
 72
hr
 1389 5372 5905 0.9099 0.9116
MCF7 GSK1059615
0.12
uM
LJP6
 72
hr
 1389 4636 5445 0.8505 0.8406
MCF7 GSK1059615
0.37
uM
LJP5
 72
hr
 1389 4309 5905 0.7283 0.7157
MCF7 GSK1059615
0.37
uM
LJP6
 72
hr
 1389 3382 5445 0.6215 0.5704
MCF7 GSK1059615
1.11
uM
LJP5
 72
hr
 1389 2462 5905 0.4159 0.3110
MCF7 GSK1059615
1.11
uM
LJP6
 72
hr
 1389 2286 5445 0.4200 0.2869
MCF7 GSK1059615
3.33
uM
LJP5
 72
hr
 1389 1373 5905 0.2326 -0.0055
MCF7 GSK1059615
3.33
uM
LJP6
 72
hr
 1389 1711 5445 0.3142 0.1104
MCF7 GSK1059615
10
uM
LJP5
 72
hr
 1389 1167 5905 0.1974 -0.0811
MCF7 GSK1059615
10
uM
LJP6
 72
hr
 1389 1060 5445 0.1945 -0.1299
MCF7 Brivanib
0.04
uM
LJP5
 72
hr
 1389 5347 5905 0.9055 0.9071
MCF7 Brivanib
0.12
uM
LJP5
 72
hr
 1389 5251 5905 0.8878 0.8868
MCF7 Brivanib
0.37
uM
LJP5
 72
hr
 1389 5637 5905 0.9545 0.9557
MCF7 Brivanib
1.11
uM
LJP5
 72
hr
 1389 5582 5905 0.9454 0.9469
MCF7 Brivanib
3.33
uM
LJP5
 72
hr
 1389 5732 5905 0.9707 0.9718
MCF7 Brivanib
10
uM
LJP5
 72
hr
 1389 5061 5905 0.8565 0.8564
MCF7 CHIR-99021
0.04
uM
LJP6
 72
hr
 1389 4320 5445 0.7878 0.7573
MCF7 CHIR-99021
0.12
uM
LJP6
 72
hr
 1389 4171 5445 0.7600 0.7214
MCF7 CHIR-99021
0.37
uM
LJP6
 72
hr
 1389 4034 5445 0.7352 0.6959
MCF7 CHIR-99021
1.11
uM
LJP6
 72
hr
 1389 3139 5445 0.5724 0.4957
MCF7 CHIR-99021
3.33
uM
LJP6
 72
hr
 1389 3384 5445 0.6164 0.5502
MCF7 CHIR-99021
10
uM
LJP6
 72
hr
 1389 2034 5445 0.3718 0.2058
MCF7 Linifanib
0.04
uM
LJP6
 72
hr
 1389 5459 5445 1.0031 1.0034