LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Sigma A6730 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 4423 | 5752 | 0.7690 | 0.6000 |
| SK-BR-3 | Sigma A6730 | 10 | uM | LJP5 | 72 | hr | 2543 | 3338 | 5752 | 0.5804 | 0.2598 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 6253 | 5752 | 1.0871 | 1.1469 |
| SK-BR-3 | WH-4-025 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5617 | 5752 | 0.9765 | 0.9601 |
| SK-BR-3 | WH-4-025 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5334 | 5752 | 0.9274 | 0.8760 |
| SK-BR-3 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5260 | 5752 | 0.9145 | 0.8537 |
| SK-BR-3 | WH-4-025 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 4894 | 5752 | 0.8508 | 0.7431 |
| SK-BR-3 | WH-4-025 | 10 | uM | LJP5 | 72 | hr | 2543 | 1680 | 5752 | 0.2920 | -0.2981 |
| SK-BR-3 | R406 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5331 | 5418 | 0.9846 | 0.9731 |
| SK-BR-3 | R406 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5197 | 5418 | 0.9598 | 0.9272 |
| SK-BR-3 | R406 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5319 | 5418 | 0.9818 | 0.9667 |
| SK-BR-3 | R406 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 5424 | 5418 | 1.0016 | 1.0042 |
| SK-BR-3 | R406 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 5508 | 5418 | 1.0177 | 1.0347 |
| SK-BR-3 | R406 | 10 | uM | LJP6 | 72 | hr | 2543 | 4380 | 5418 | 0.8090 | 0.6477 |
| SK-BR-3 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 1493 | 5418 | 0.2753 | -0.3872 |
| SK-BR-3 | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1559 | 5418 | 0.2877 | -0.3621 |
| SK-BR-3 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1517 | 5418 | 0.2799 | -0.3779 |
| SK-BR-3 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1439 | 5418 | 0.2657 | -0.4071 |
| SK-BR-3 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1481 | 5418 | 0.2732 | -0.3916 |
| SK-BR-3 | BI-2536 | 10 | uM | LJP6 | 72 | hr | 2543 | 1198 | 5418 | 0.2210 | -0.4991 |
| SK-BR-3 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 1613 | 5418 | 0.2978 | -0.3416 |
| SK-BR-3 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1373 | 5418 | 0.2534 | -0.4322 |
| SK-BR-3 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1321 | 5418 | 0.2439 | -0.4518 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1204 | 5418 | 0.2225 | -0.4962 |
| SK-BR-3 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1182 | 5418 | 0.2179 | -0.5053 |