LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5792 | 5752 | 1.0069 | 1.0117 |
| SK-BR-3 | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5427 | 5752 | 0.9434 | 0.9032 |
| SK-BR-3 | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 5005 | 5752 | 0.8701 | 0.7770 |
| SK-BR-3 | YM 201636 | 10 | uM | LJP5 | 72 | hr | 2543 | 3011 | 5752 | 0.5236 | 0.1541 |
| SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5944 | 5752 | 1.0335 | 1.0568 |
| SK-BR-3 | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5472 | 5752 | 0.9513 | 0.9170 |
| SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 6082 | 5752 | 1.0573 | 1.0966 |
| SK-BR-3 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5977 | 5752 | 1.0392 | 1.0664 |
| SK-BR-3 | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 3792 | 5752 | 0.6594 | 0.4025 |
| SK-BR-3 | TWS119 | 10 | uM | LJP5 | 72 | hr | 2543 | 1147 | 5752 | 0.1994 | -0.4923 |
| SK-BR-3 | PF477736 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 1896 | 5752 | 0.3297 | -0.2209 |
| SK-BR-3 | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 1652 | 5752 | 0.2872 | -0.3070 |
| SK-BR-3 | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1575 | 5752 | 0.2738 | -0.3345 |
| SK-BR-3 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1519 | 5752 | 0.2640 | -0.3548 |
| SK-BR-3 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1573 | 5752 | 0.2735 | -0.3354 |
| SK-BR-3 | PF477736 | 10 | uM | LJP5 | 72 | hr | 2543 | 1353 | 5752 | 0.2353 | -0.4148 |
| SK-BR-3 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5730 | 5752 | 0.9963 | 0.9936 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5820 | 5752 | 1.0118 | 1.0200 |
| SK-BR-3 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5986 | 5752 | 1.0407 | 1.0690 |
| SK-BR-3 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5893 | 5752 | 1.0246 | 1.0412 |
| SK-BR-3 | LDN-193189 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 3065 | 5752 | 0.5330 | 0.1696 |
| SK-BR-3 | LDN-193189 | 10 | uM | LJP5 | 72 | hr | 2543 | 768 | 5752 | 0.1337 | -0.6393 |
| SK-BR-3 | PF431396 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5789 | 5752 | 1.0064 | 1.0109 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4706 | 5752 | 0.8182 | 0.6862 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 3422 | 5752 | 0.5950 | 0.2866 |