LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5400 | 5418 | 0.9980 | 0.9994 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5248 | 5752 | 0.9124 | 0.8502 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5325 | 5418 | 0.9844 | 0.9747 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5303 | 5752 | 0.9219 | 0.8664 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5238 | 5418 | 0.9675 | 0.9419 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 4778 | 5752 | 0.8306 | 0.7079 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4749 | 5418 | 0.8769 | 0.7734 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 3638 | 5752 | 0.6326 | 0.3551 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 3929 | 5418 | 0.7259 | 0.4917 |
| SK-BR-3 | PD0325901 | 10 | uM | LJP5 | 72 | hr | 2543 | 2519 | 5752 | 0.4381 | -0.0119 |
| SK-BR-3 | PD0325901 | 10 | uM | LJP6 | 72 | hr | 2543 | 3118 | 5418 | 0.5752 | 0.2034 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 2543 | 2298 | 5752 | 0.3995 | -0.0827 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2263 | 5418 | 0.4181 | -0.1011 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 2543 | 1929 | 5752 | 0.3354 | -0.2097 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 2543 | 2073 | 5418 | 0.3833 | -0.1702 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2165 | 5752 | 0.3765 | -0.1278 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2065 | 5418 | 0.3817 | -0.1734 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2371 | 5752 | 0.4122 | -0.0580 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2174 | 5418 | 0.4021 | -0.1330 |
| SK-BR-3 | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1576 | 5752 | 0.2740 | -0.3344 |
| SK-BR-3 | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1722 | 5418 | 0.3179 | -0.3010 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 2543 | 837 | 5752 | 0.1456 | -0.6121 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 2543 | 1120 | 5418 | 0.2066 | -0.5290 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 6054 | 5752 | 1.0526 | 1.0890 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5952 | 5752 | 1.0348 | 1.0591 |