LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 72 | hr | 1389 | 297 | 5445 | 0.0548 | -0.5439 |
| MCF7 | Pelitinib | 0.04 | uM | LJP5 | 72 | hr | 1389 | 5916 | 5905 | 1.0028 | 1.0029 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5611 | 5905 | 0.9467 | 0.9398 |
| MCF7 | Pelitinib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5272 | 5905 | 0.8922 | 0.8930 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4980 | 5905 | 0.8423 | 0.8408 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 3172 | 5905 | 0.5362 | 0.4818 |
| MCF7 | Pelitinib | 10 | uM | LJP5 | 72 | hr | 1389 | 782 | 5905 | 0.1325 | -0.2405 |
| MCF7 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 1389 | 1470 | 5905 | 0.2486 | 0.0260 |
| MCF7 | Luminespib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 1395 | 5905 | 0.2365 | 0.0023 |
| MCF7 | Luminespib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 1368 | 5905 | 0.2315 | -0.0080 |
| MCF7 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1301 | 5905 | 0.2204 | -0.0309 |
| MCF7 | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 1467 | 5905 | 0.2485 | 0.0264 |
| MCF7 | Luminespib | 10 | uM | LJP5 | 72 | hr | 1389 | 1340 | 5905 | 0.2269 | -0.0173 |
| MCF7 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 2293 | 5905 | 0.3881 | 0.2706 |
| MCF7 | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 2430 | 5905 | 0.4111 | 0.3058 |
| MCF7 | AZD8330 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 2405 | 5905 | 0.4079 | 0.3011 |
| MCF7 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 2936 | 5905 | 0.4974 | 0.4313 |
| MCF7 | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 2688 | 5905 | 0.4554 | 0.3720 |
| MCF7 | AZD8330 | 10 | uM | LJP5 | 72 | hr | 1389 | 3004 | 5905 | 0.5090 | 0.4472 |
| MCF7 | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 4677 | 5905 | 0.7915 | 0.7874 |
| MCF7 | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5067 | 5905 | 0.8571 | 0.8564 |
| MCF7 | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5755 | 5905 | 0.9740 | 0.9743 |
| MCF7 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6009 | 5905 | 1.0177 | 1.0169 |
| MCF7 | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 4176 | 5905 | 0.7064 | 0.6921 |
| MCF7 | TGX221 | 10 | uM | LJP5 | 72 | hr | 1389 | 5124 | 5905 | 0.8662 | 0.8647 |