LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 1641 | 5905 | 0.2778 | 0.0827 |
MCF7 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 1458 | 5905 | 0.2467 | 0.0226 |
MCF7 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1352 | 5905 | 0.2288 | -0.0138 |
MCF7 | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 1322 | 5905 | 0.2236 | -0.0244 |
MCF7 | Torin2 | 10 | uM | LJP5 | 72 | hr | 1389 | 1122 | 5905 | 0.1901 | -0.0973 |
MCF7 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 3933 | 5445 | 0.7218 | 0.6937 |
MCF7 | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4235 | 5445 | 0.7766 | 0.7572 |
MCF7 | WZ-4-145 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 3794 | 5445 | 0.6957 | 0.6618 |
MCF7 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2885 | 5445 | 0.5306 | 0.4496 |
MCF7 | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 2662 | 5445 | 0.4893 | 0.3909 |
MCF7 | WZ-4-145 | 10 | uM | LJP6 | 72 | hr | 1389 | 579 | 5445 | 0.1064 | -0.3595 |
MCF7 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 544 | 5905 | 0.0917 | -0.3656 |
MCF7 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 485 | 5905 | 0.0822 | -0.3957 |
MCF7 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 503 | 5905 | 0.0853 | -0.3853 |
MCF7 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 577 | 5905 | 0.0976 | -0.3443 |
MCF7 | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 614 | 5905 | 0.1040 | -0.3239 |
MCF7 | WZ3105 | 10 | uM | LJP5 | 72 | hr | 1389 | 562 | 5905 | 0.0956 | -0.3530 |
MCF7 | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 4718 | 5445 | 0.8595 | 0.8378 |
MCF7 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4496 | 5445 | 0.8209 | 0.8002 |
MCF7 | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 3653 | 5445 | 0.6673 | 0.6204 |
MCF7 | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2574 | 5445 | 0.4705 | 0.3576 |
MCF7 | XMD11-50 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 2022 | 5445 | 0.3699 | 0.2037 |
MCF7 | XMD11-50 | 10 | uM | LJP6 | 72 | hr | 1389 | 1481 | 5445 | 0.2704 | 0.0254 |
MCF7 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 1389 | 3914 | 5445 | 0.7153 | 0.6814 |
MCF7 | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4450 | 5445 | 0.8130 | 0.7892 |