LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 PHA-793887
0.04
uM
LJP6
 72
hr
 1389 2290 5445 0.4211 0.2888
MCF7 PHA-793887
0.12
uM
LJP6
 72
hr
 1389 2180 5445 0.4005 0.2563
MCF7 PHA-793887
0.37
uM
LJP6
 72
hr
 1389 1696 5445 0.3119 0.1064
MCF7 PHA-793887
1.11
uM
LJP6
 72
hr
 1389 1507 5445 0.2767 0.0411
MCF7 PHA-793887
3.33
uM
LJP6
 72
hr
 1389 1357 5445 0.2487 -0.0143
MCF7 PHA-793887
10
uM
LJP6
 72
hr
 1389 578 5445 0.1063 -0.3600
MCF7 QL-X-138
0.04
uM
LJP6
 72
hr
 1389 3387 5445 0.6226 0.5715
MCF7 QL-X-138
0.12
uM
LJP6
 72
hr
 1389 3314 5445 0.6096 0.5556
MCF7 QL-X-138
0.37
uM
LJP6
 72
hr
 1389 2730 5445 0.5009 0.4070
MCF7 QL-X-138
1.11
uM
LJP6
 72
hr
 1389 2395 5445 0.4384 0.3129
MCF7 QL-X-138
3.33
uM
LJP6
 72
hr
 1389 2037 5445 0.3734 0.2115
MCF7 QL-X-138
10
uM
LJP6
 72
hr
 1389 1134 5445 0.2086 -0.0981
MCF7 QL-XII-47
0.04
uM
LJP6
 72
hr
 1389 4059 5445 0.7404 0.7067
MCF7 QL-XII-47
0.12
uM
LJP6
 72
hr
 1389 3723 5445 0.6823 0.6403
MCF7 QL-XII-47
0.37
uM
LJP6
 72
hr
 1389 1728 5445 0.3173 0.1160
MCF7 QL-XII-47
1.11
uM
LJP6
 72
hr
 1389 1257 5445 0.2308 -0.0510
MCF7 QL-XII-47
3.33
uM
LJP6
 72
hr
 1389 1122 5445 0.2059 -0.1049
MCF7 QL-XII-47
10
uM
LJP6
 72
hr
 1389 1074 5445 0.1966 -0.1261
MCF7 Torin1
0.04
uM
LJP6
 72
hr
 1389 1882 5445 0.3460 0.1663
MCF7 Torin1
0.12
uM
LJP6
 72
hr
 1389 1804 5445 0.3313 0.1408
MCF7 Torin1
0.37
uM
LJP6
 72
hr
 1389 1754 5445 0.3217 0.1233
MCF7 Torin1
1.11
uM
LJP6
 72
hr
 1389 1569 5445 0.2889 0.0639
MCF7 Torin1
3.33
uM
LJP6
 72
hr
 1389 1459 5445 0.2683 0.0250
MCF7 Torin1
10
uM
LJP6
 72
hr
 1389 1257 5445 0.2308 -0.0508
MCF7 Torin2
0.04
uM
LJP5
 72
hr
 1389 1493 5905 0.2525 0.0337