LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Barasertib
10
uM
LJP5
 72
hr
 1389 1663 5905 0.2820 0.0904
MCF7 Vemurafenib
0.04
uM
LJP5
 72
hr
 1389 5823 5905 0.9859 0.9864
MCF7 Vemurafenib
0.12
uM
LJP5
 72
hr
 1389 5909 5905 1.0012 1.0013
MCF7 Vemurafenib
0.37
uM
LJP5
 72
hr
 1389 6152 5905 1.0425 1.0406
MCF7 Vemurafenib
1.11
uM
LJP5
 72
hr
 1389 6263 5905 1.0611 1.0579
MCF7 Vemurafenib
3.33
uM
LJP5
 72
hr
 1389 5927 5905 1.0052 1.0049
MCF7 Vemurafenib
10
uM
LJP5
 72
hr
 1389 5618 5905 0.9517 0.9533
MCF7 Enzastaurin
0.04
uM
LJP5
 72
hr
 1389 6139 5905 1.0394 1.0373
MCF7 Enzastaurin
0.12
uM
LJP5
 72
hr
 1389 5864 5905 0.9938 0.9942
MCF7 Enzastaurin
0.37
uM
LJP5
 72
hr
 1389 6125 5905 1.0364 1.0338
MCF7 Enzastaurin
1.11
uM
LJP5
 72
hr
 1389 5842 5905 0.9887 0.9886
MCF7 Enzastaurin
3.33
uM
LJP5
 72
hr
 1389 6070 5905 1.0269 1.0244
MCF7 Enzastaurin
10
uM
LJP5
 72
hr
 1389 6072 5905 1.0283 1.0270
MCF7 Palbociclib
0.04
uM
LJP6
 72
hr
 1389 4400 5445 0.8075 0.7926
MCF7 Palbociclib
0.12
uM
LJP6
 72
hr
 1389 3951 5445 0.7250 0.6976
MCF7 Palbociclib
0.37
uM
LJP6
 72
hr
 1389 3632 5445 0.6662 0.6259
MCF7 Palbociclib
1.11
uM
LJP6
 72
hr
 1389 3058 5445 0.5622 0.4926
MCF7 Palbociclib
3.33
uM
LJP6
 72
hr
 1389 2633 5445 0.4835 0.3822
MCF7 Palbociclib
10
uM
LJP6
 72
hr
 1389 2357 5445 0.4325 0.3057
MCF7 PF562271
0.04
uM
LJP6
 72
hr
 1389 4722 5445 0.8668 0.8594
MCF7 PF562271
0.12
uM
LJP6
 72
hr
 1389 4397 5445 0.8077 0.7942
MCF7 PF562271
0.37
uM
LJP6
 72
hr
 1389 3527 5445 0.6477 0.6036
MCF7 PF562271
1.11
uM
LJP6
 72
hr
 1389 2503 5445 0.4590 0.3457
MCF7 PF562271
3.33
uM
LJP6
 72
hr
 1389 1233 5445 0.2267 -0.0590
MCF7 PF562271
10
uM
LJP6
 72
hr
 1389 532 5445 0.0972 -0.3885