LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 AZD-6482
3.33
uM
LJP5
 72
hr
 1389 4380 5905 0.7408 0.7310
MCF7 AZD-6482
10
uM
LJP5
 72
hr
 1389 1957 5905 0.3309 0.1761
MCF7 NU7441
0.04
uM
LJP5
 72
hr
 1389 6255 5905 1.0608 1.0573
MCF7 NU7441
0.12
uM
LJP5
 72
hr
 1389 5677 5905 0.9624 0.9637
MCF7 NU7441
0.37
uM
LJP5
 72
hr
 1389 5519 5905 0.9336 0.9339
MCF7 NU7441
1.11
uM
LJP5
 72
hr
 1389 5906 5905 1.0024 1.0013
MCF7 NU7441
3.33
uM
LJP5
 72
hr
 1389 5117 5905 0.8677 0.8684
MCF7 NU7441
10
uM
LJP5
 72
hr
 1389 3490 5905 0.5918 0.5554
MCF7 OSI-027
0.04
uM
LJP6
 72
hr
 1389 5485 5445 1.0072 1.0073
MCF7 OSI-027
0.12
uM
LJP6
 72
hr
 1389 4017 5445 0.7386 0.7131
MCF7 OSI-027
0.37
uM
LJP6
 72
hr
 1389 2848 5445 0.5229 0.4382
MCF7 OSI-027
1.11
uM
LJP6
 72
hr
 1389 2175 5445 0.3993 0.2544
MCF7 OSI-027
3.33
uM
LJP6
 72
hr
 1389 2141 5445 0.3935 0.2451
MCF7 OSI-027
10
uM
LJP6
 72
hr
 1389 1894 5445 0.3486 0.1707
MCF7 WYE-125132
0.04
uM
LJP6
 72
hr
 1389 1958 5445 0.3614 0.1917
MCF7 WYE-125132
0.12
uM
LJP6
 72
hr
 1389 1919 5445 0.3532 0.1784
MCF7 WYE-125132
0.37
uM
LJP6
 72
hr
 1389 1854 5445 0.3416 0.1586
MCF7 WYE-125132
1.11
uM
LJP6
 72
hr
 1389 1894 5445 0.3490 0.1713
MCF7 WYE-125132
3.33
uM
LJP6
 72
hr
 1389 1701 5445 0.3129 0.1083
MCF7 WYE-125132
10
uM
LJP6
 72
hr
 1389 1652 5445 0.3039 0.0920
MCF7 Barasertib
0.04
uM
LJP5
 72
hr
 1389 2234 5905 0.3783 0.2554
MCF7 Barasertib
0.12
uM
LJP5
 72
hr
 1389 1796 5905 0.3043 0.1311
MCF7 Barasertib
0.37
uM
LJP5
 72
hr
 1389 1687 5905 0.2858 0.0975
MCF7 Barasertib
1.11
uM
LJP5
 72
hr
 1389 1814 5905 0.3069 0.1354
MCF7 Barasertib
3.33
uM
LJP5
 72
hr
 1389 1739 5905 0.2941 0.1121