LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PF477736 | 10 | uM | LJP5 | 72 | hr | 1389 | 1495 | 5905 | 0.2534 | 0.0360 |
| MCF7 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 6186 | 5905 | 1.0473 | 1.0446 |
| MCF7 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5484 | 5905 | 0.9282 | 0.9294 |
| MCF7 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5764 | 5905 | 0.9757 | 0.9763 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5282 | 5905 | 0.8945 | 0.8959 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 3320 | 5905 | 0.5621 | 0.5175 |
| MCF7 | LDN-193189 | 10 | uM | LJP5 | 72 | hr | 1389 | 536 | 5905 | 0.0909 | -0.3661 |
| MCF7 | PF431396 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 4828 | 5905 | 0.8175 | 0.8158 |
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 3602 | 5905 | 0.6098 | 0.5778 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 2289 | 5905 | 0.3872 | 0.2685 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1589 | 5905 | 0.2686 | 0.0640 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 1405 | 5905 | 0.2378 | 0.0048 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 72 | hr | 1389 | 665 | 5905 | 0.1127 | -0.2973 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1389 | 6120 | 5445 | 1.1282 | 1.1277 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 1389 | 5607 | 5445 | 1.0295 | 1.0296 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 72 | hr | 1389 | 3634 | 5445 | 0.6688 | 0.6292 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 1389 | 2084 | 5445 | 0.3847 | 0.2299 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1322 | 5445 | 0.2422 | -0.0275 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 72 | hr | 1389 | 1046 | 5445 | 0.1914 | -0.1399 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 6419 | 5905 | 1.0870 | 1.0816 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5985 | 5905 | 1.0136 | 1.0130 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5969 | 5905 | 1.0111 | 1.0107 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4937 | 5905 | 0.8350 | 0.8330 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 4553 | 5905 | 0.7704 | 0.7641 |
| MCF7 | SU11274 | 10 | uM | LJP5 | 72 | hr | 1389 | 1689 | 5905 | 0.2859 | 0.0974 |