LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1510 | 5445 | 0.2772 | 0.0418 |
| MCF7 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1446 | 5445 | 0.2652 | 0.0182 |
| MCF7 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1412 | 5445 | 0.2594 | 0.0075 |
| MCF7 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1341 | 5445 | 0.2464 | -0.0191 |
| MCF7 | BI-2536 | 10 | uM | LJP6 | 72 | hr | 1389 | 912 | 5445 | 0.1676 | -0.1930 |
| MCF7 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 1385 | 5445 | 0.2540 | -0.0037 |
| MCF7 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1052 | 5445 | 0.1933 | -0.1323 |
| MCF7 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 886 | 5445 | 0.1622 | -0.2067 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 804 | 5445 | 0.1473 | -0.2445 |
| MCF7 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 803 | 5445 | 0.1477 | -0.2433 |
| MCF7 | A443654 | 10 | uM | LJP6 | 72 | hr | 1389 | 547 | 5445 | 0.1004 | -0.3780 |
| MCF7 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 5303 | 5905 | 0.8986 | 0.9003 |
| MCF7 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5500 | 5905 | 0.9327 | 0.9342 |
| MCF7 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5754 | 5905 | 0.9738 | 0.9741 |
| MCF7 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 6309 | 5905 | 1.0699 | 1.0657 |
| MCF7 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 6498 | 5905 | 1.1011 | 1.0947 |
| MCF7 | SB590885 | 10 | uM | LJP5 | 72 | hr | 1389 | 4408 | 5905 | 0.7448 | 0.7334 |
| MCF7 | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 1389 | 2668 | 5445 | 0.4891 | 0.3892 |
| MCF7 | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 2178 | 5445 | 0.4001 | 0.2554 |
| MCF7 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1601 | 5445 | 0.2937 | 0.0728 |
| MCF7 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1383 | 5445 | 0.2537 | -0.0042 |
| MCF7 | Pictilisib | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1289 | 5445 | 0.2364 | -0.0391 |
| MCF7 | Pictilisib | 10 | uM | LJP6 | 72 | hr | 1389 | 1215 | 5445 | 0.2233 | -0.0666 |
| MCF7 | PD184352 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 6167 | 5905 | 1.0438 | 1.0411 |
| MCF7 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5122 | 5905 | 0.8672 | 0.8679 |