LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GSK1904529A
0.37
uM
LJP6
 72
hr
 1694 6649 11217 0.5929 0.6508
MCF 10A GSK1904529A
1.11
uM
LJP6
 72
hr
 1694 6263 11217 0.5585 0.6152
MCF 10A GSK1904529A
3.33
uM
LJP6
 72
hr
 1694 6293 11217 0.5609 0.6174
MCF 10A GSK1904529A
10
uM
LJP6
 72
hr
 1694 6329 11217 0.5643 0.6214
MCF 10A Linsitinib
0.04
uM
LJP5
 72
hr
 1694 10398 11103 0.9365 0.9522
MCF 10A Linsitinib
0.12
uM
LJP5
 72
hr
 1694 9752 11103 0.8783 0.9066
MCF 10A Linsitinib
0.37
uM
LJP5
 72
hr
 1694 9053 11103 0.8154 0.8549
MCF 10A Linsitinib
1.11
uM
LJP5
 72
hr
 1694 8544 11103 0.7695 0.8158
MCF 10A Linsitinib
3.33
uM
LJP5
 72
hr
 1694 7909 11103 0.7124 0.7649
MCF 10A Linsitinib
10
uM
LJP5
 72
hr
 1694 6268 11103 0.5646 0.6198
MCF 10A Ruxolitinib
0.04
uM
LJP5
 72
hr
 1694 10858 11103 0.9779 0.9836
MCF 10A Ruxolitinib
0.12
uM
LJP5
 72
hr
 1694 11068 11103 0.9969 0.9975
MCF 10A Ruxolitinib
0.37
uM
LJP5
 72
hr
 1694 10910 11103 0.9826 0.9870
MCF 10A Ruxolitinib
1.11
uM
LJP5
 72
hr
 1694 10633 11103 0.9577 0.9684
MCF 10A Ruxolitinib
3.33
uM
LJP5
 72
hr
 1694 10614 11103 0.9559 0.9670
MCF 10A Ruxolitinib
10
uM
LJP5
 72
hr
 1694 9296 11103 0.8372 0.8728
MCF 10A Momelotinib
0.04
uM
LJP5
 72
hr
 1694 10543 11103 0.9495 0.9622
MCF 10A Momelotinib
0.12
uM
LJP5
 72
hr
 1694 10139 11103 0.9132 0.9341
MCF 10A Momelotinib
0.37
uM
LJP5
 72
hr
 1694 9410 11103 0.8476 0.8816
MCF 10A Momelotinib
1.11
uM
LJP5
 72
hr
 1694 8936 11103 0.8049 0.8461
MCF 10A Momelotinib
3.33
uM
LJP5
 72
hr
 1694 7845 11103 0.7065 0.7594
MCF 10A Momelotinib
10
uM
LJP5
 72
hr
 1694 2672 11103 0.2407 0.1828
MCF 10A Fedratinib
0.04
uM
LJP5
 72
hr
 1694 11139 11103 1.0032 1.0022
MCF 10A Fedratinib
0.12
uM
LJP5
 72
hr
 1694 10674 11103 0.9613 0.9710
MCF 10A Fedratinib
0.37
uM
LJP5
 72
hr
 1694 10354 11103 0.9326 0.9491