LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A AZD-6482
3.33
uM
LJP5
 72
hr
 1694 9430 11103 0.8493 0.8831
MCF 10A AZD-6482
10
uM
LJP5
 72
hr
 1694 4286 11103 0.3862 0.4047
MCF 10A NU7441
0.04
uM
LJP5
 72
hr
 1694 11501 11103 1.0359 1.0262
MCF 10A NU7441
0.12
uM
LJP5
 72
hr
 1694 11065 11103 0.9966 0.9972
MCF 10A NU7441
0.37
uM
LJP5
 72
hr
 1694 10832 11103 0.9755 0.9815
MCF 10A NU7441
1.11
uM
LJP5
 72
hr
 1694 10716 11103 0.9651 0.9738
MCF 10A NU7441
3.33
uM
LJP5
 72
hr
 1694 10125 11103 0.9119 0.9331
MCF 10A NU7441
10
uM
LJP5
 72
hr
 1694 7207 11103 0.6490 0.7050
MCF 10A OSI-027
0.04
uM
LJP6
 72
hr
 1694 10571 11217 0.9425 0.9570
MCF 10A OSI-027
0.12
uM
LJP6
 72
hr
 1694 8354 11217 0.7449 0.7952
MCF 10A OSI-027
0.37
uM
LJP6
 72
hr
 1694 6101 11217 0.5440 0.5997
MCF 10A OSI-027
1.11
uM
LJP6
 72
hr
 1694 4119 11217 0.3674 0.3846
MCF 10A OSI-027
3.33
uM
LJP6
 72
hr
 1694 3517 11217 0.3135 0.3071
MCF 10A OSI-027
10
uM
LJP6
 72
hr
 1694 2582 11217 0.2303 0.1660
MCF 10A WYE-125132
0.04
uM
LJP6
 72
hr
 1694 6905 11217 0.6156 0.6739
MCF 10A WYE-125132
0.12
uM
LJP6
 72
hr
 1694 3859 11217 0.3440 0.3522
MCF 10A WYE-125132
0.37
uM
LJP6
 72
hr
 1694 3270 11217 0.2914 0.2719
MCF 10A WYE-125132
1.11
uM
LJP6
 72
hr
 1694 2743 11217 0.2446 0.1931
MCF 10A WYE-125132
3.33
uM
LJP6
 72
hr
 1694 2780 11217 0.2478 0.1987
MCF 10A WYE-125132
10
uM
LJP6
 72
hr
 1694 2598 11217 0.2317 0.1698
MCF 10A Barasertib
0.04
uM
LJP5
 72
hr
 1694 2690 11103 0.2423 0.1845
MCF 10A Barasertib
0.12
uM
LJP5
 72
hr
 1694 1920 11103 0.1729 0.0472
MCF 10A Barasertib
0.37
uM
LJP5
 72
hr
 1694 1965 11103 0.1770 0.0562
MCF 10A Barasertib
1.11
uM
LJP5
 72
hr
 1694 1993 11103 0.1795 0.0616
MCF 10A Barasertib
3.33
uM
LJP5
 72
hr
 1694 2090 11103 0.1883 0.0804