LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A ZSTK474
1.11
uM
LJP6
 72
hr
 1694 5606 11217 0.4997 0.5499
MCF 10A ZSTK474
3.33
uM
LJP6
 72
hr
 1694 3867 11217 0.3445 0.3517
MCF 10A ZSTK474
10
uM
LJP6
 72
hr
 1694 2788 11217 0.2485 0.1997
MCF 10A BX-912
0.04
uM
LJP5
 72
hr
 1694 10337 11103 0.9313 0.9475
MCF 10A BX-912
0.12
uM
LJP5
 72
hr
 1694 10402 11103 0.9368 0.9524
MCF 10A BX-912
0.37
uM
LJP5
 72
hr
 1694 8956 11103 0.8067 0.8476
MCF 10A BX-912
1.11
uM
LJP5
 72
hr
 1694 2557 11103 0.2304 0.1640
MCF 10A BX-912
3.33
uM
LJP5
 72
hr
 1694 2250 11103 0.2027 0.1103
MCF 10A BX-912
10
uM
LJP5
 72
hr
 1694 1956 11103 0.1762 0.0543
MCF 10A Selumetinib
0.04
uM
LJP6
 72
hr
 1694 6318 11217 0.5631 0.6196
MCF 10A Selumetinib
0.12
uM
LJP6
 72
hr
 1694 4842 11217 0.4316 0.4690
MCF 10A Selumetinib
0.37
uM
LJP6
 72
hr
 1694 3915 11217 0.3490 0.3594
MCF 10A Selumetinib
1.11
uM
LJP6
 72
hr
 1694 3467 11217 0.3091 0.3000
MCF 10A Selumetinib
3.33
uM
LJP6
 72
hr
 1694 3276 11217 0.2920 0.2734
MCF 10A Selumetinib
10
uM
LJP6
 72
hr
 1694 2916 11217 0.2599 0.2198
MCF 10A MK2206
0.04
uM
LJP6
 72
hr
 1694 11562 11217 1.0307 1.0223
MCF 10A MK2206
0.12
uM
LJP6
 72
hr
 1694 11362 11217 1.0129 1.0093
MCF 10A MK2206
0.37
uM
LJP6
 72
hr
 1694 7386 11217 0.6584 0.7157
MCF 10A MK2206
1.11
uM
LJP6
 72
hr
 1694 10727 11217 0.9563 0.9675
MCF 10A MK2206
3.33
uM
LJP6
 72
hr
 1694 10046 11217 0.8957 0.9208
MCF 10A MK2206
10
uM
LJP6
 72
hr
 1694 5446 11217 0.4853 0.5332
MCF 10A AZD-6482
0.04
uM
LJP5
 72
hr
 1694 11212 11103 1.0098 1.0071
MCF 10A AZD-6482
0.12
uM
LJP5
 72
hr
 1694 10786 11103 0.9714 0.9786
MCF 10A AZD-6482
0.37
uM
LJP5
 72
hr
 1694 10494 11103 0.9452 0.9589
MCF 10A AZD-6482
1.11
uM
LJP5
 72
hr
 1694 9840 11103 0.8862 0.9128