LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A PD184352
0.37
uM
LJP5
 72
hr
 1694 4821 11103 0.4342 0.4702
MCF 10A PD184352
1.11
uM
LJP5
 72
hr
 1694 4073 11103 0.3668 0.3813
MCF 10A PD184352
3.33
uM
LJP5
 72
hr
 1694 3347 11103 0.3014 0.2853
MCF 10A PD184352
10
uM
LJP5
 72
hr
 1694 3034 11103 0.2733 0.2397
MCF 10A PLX-4720
0.04
uM
LJP5
 72
hr
 1694 11201 11103 1.0088 1.0065
MCF 10A PLX-4720
0.12
uM
LJP5
 72
hr
 1694 11028 11103 0.9933 0.9949
MCF 10A PLX-4720
0.37
uM
LJP5
 72
hr
 1694 10909 11103 0.9827 0.9870
MCF 10A PLX-4720
1.11
uM
LJP5
 72
hr
 1694 11583 11103 1.0433 1.0314
MCF 10A PLX-4720
3.33
uM
LJP5
 72
hr
 1694 12034 11103 1.0839 1.0602
MCF 10A PLX-4720
10
uM
LJP5
 72
hr
 1694 10314 11103 0.9289 0.9457
MCF 10A Lapatinib
0.04
uM
LJP6
 72
hr
 1694 10844 11217 0.9667 0.9753
MCF 10A Lapatinib
0.12
uM
LJP6
 72
hr
 1694 10440 11217 0.9308 0.9481
MCF 10A Lapatinib
0.37
uM
LJP6
 72
hr
 1694 10095 11217 0.9001 0.9243
MCF 10A Lapatinib
1.11
uM
LJP6
 72
hr
 1694 9605 11217 0.8563 0.8894
MCF 10A Lapatinib
3.33
uM
LJP6
 72
hr
 1694 8365 11217 0.7457 0.7959
MCF 10A Lapatinib
10
uM
LJP6
 72
hr
 1694 4508 11217 0.4018 0.4314
MCF 10A Sirolimus
0.04
uM
LJP6
 72
hr
 1694 12244 11217 1.0916 1.0653
MCF 10A Sirolimus
0.12
uM
LJP6
 72
hr
 1694 12338 11217 1.0999 1.0710
MCF 10A Sirolimus
0.37
uM
LJP6
 72
hr
 1694 12534 11217 1.1174 1.0831
MCF 10A Sirolimus
1.11
uM
LJP6
 72
hr
 1694 12479 11217 1.1126 1.0798
MCF 10A Sirolimus
3.33
uM
LJP6
 72
hr
 1694 12704 11217 1.1326 1.0934
MCF 10A Sirolimus
10
uM
LJP6
 72
hr
 1694 12441 11217 1.1091 1.0774
MCF 10A ZSTK474
0.04
uM
LJP6
 72
hr
 1694 10958 11217 0.9768 0.9828
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 1694 9950 11217 0.8870 0.9138
MCF 10A ZSTK474
0.37
uM
LJP6
 72
hr
 1694 8257 11217 0.7361 0.7874