LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Dactolisib
3.33
uM
LJP5
 72
hr
 765 853 3148 0.2712 0.0551
Hs 578T Dactolisib
10
uM
LJP5
 72
hr
 765 893 3148 0.2838 0.0787
Hs 578T Alpelisib
0.04
uM
LJP5
 72
hr
 765 3014 3148 0.9574 0.9577
Hs 578T Alpelisib
0.12
uM
LJP5
 72
hr
 765 2884 3148 0.9163 0.9162
Hs 578T Alpelisib
0.37
uM
LJP5
 72
hr
 765 2660 3148 0.8451 0.8414
Hs 578T Alpelisib
1.11
uM
LJP5
 72
hr
 765 2571 3148 0.8169 0.8112
Hs 578T Alpelisib
3.33
uM
LJP5
 72
hr
 765 2409 3148 0.7652 0.7539
Hs 578T Alpelisib
10
uM
LJP5
 72
hr
 765 1757 3148 0.5581 0.5029
Hs 578T GDC-0980
0.04
uM
LJP5
 72
hr
 765 2218 3148 0.7046 0.6846
Hs 578T GDC-0980
0.12
uM
LJP5
 72
hr
 765 1475 3148 0.4686 0.3794
Hs 578T GDC-0980
0.37
uM
LJP5
 72
hr
 765 1076 3148 0.3419 0.1819
Hs 578T GDC-0980
1.11
uM
LJP5
 72
hr
 765 882 3148 0.2802 0.0720
Hs 578T GDC-0980
3.33
uM
LJP5
 72
hr
 765 805 3148 0.2557 0.0251
Hs 578T GDC-0980
10
uM
LJP5
 72
hr
 765 728 3148 0.2314 -0.0238
Hs 578T Mitoxantrone
0.04
uM
LJP5
 72
hr
 765 836 3148 0.2658 0.0448
Hs 578T Mitoxantrone
0.04
uM
LJP6
 72
hr
 765 807 3101 0.2603 0.0268
Hs 578T Mitoxantrone
0.12
uM
LJP5
 72
hr
 765 698 3148 0.2219 -0.0437
Hs 578T Mitoxantrone
0.12
uM
LJP6
 72
hr
 765 669 3101 0.2156 -0.0645
Hs 578T Mitoxantrone
0.37
uM
LJP5
 72
hr
 765 628 3148 0.1995 -0.0923
Hs 578T Mitoxantrone
0.37
uM
LJP6
 72
hr
 765 661 3101 0.2132 -0.0696
Hs 578T Mitoxantrone
1.11
uM
LJP5
 72
hr
 765 448 3148 0.1424 -0.2309
Hs 578T Mitoxantrone
1.11
uM
LJP6
 72
hr
 765 434 3101 0.1399 -0.2450
Hs 578T Mitoxantrone
3.33
uM
LJP5
 72
hr
 765 189 3148 0.0601 -0.4956
Hs 578T Mitoxantrone
3.33
uM
LJP6
 72
hr
 765 212 3101 0.0687 -0.4709
Hs 578T Mitoxantrone
10
uM
LJP5
 72
hr
 765 172 3148 0.0546 -0.5188