LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | Mitoxantrone | 10 | uM | LJP6 | 72 | hr | 765 | 208 | 3101 | 0.0672 | -0.4763 |
Hs 578T | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 765 | 3225 | 3148 | 1.0245 | 1.0238 |
Hs 578T | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 765 | 3176 | 3101 | 1.0238 | 1.0232 |
Hs 578T | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 765 | 3174 | 3148 | 1.0083 | 1.0081 |
Hs 578T | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 765 | 3142 | 3101 | 1.0129 | 1.0127 |
Hs 578T | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 765 | 2518 | 3148 | 0.7998 | 0.7921 |
Hs 578T | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 765 | 2454 | 3101 | 0.7908 | 0.7772 |
Hs 578T | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 765 | 1495 | 3148 | 0.4750 | 0.3874 |
Hs 578T | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 765 | 1414 | 3101 | 0.4552 | 0.3483 |
Hs 578T | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 765 | 920 | 3148 | 0.2924 | 0.0950 |
Hs 578T | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 765 | 865 | 3101 | 0.2787 | 0.0607 |
Hs 578T | Radicicol | 10 | uM | LJP5 | 72 | hr | 765 | 693 | 3148 | 0.2202 | -0.0476 |
Hs 578T | Radicicol | 10 | uM | LJP6 | 72 | hr | 765 | 748 | 3101 | 0.2413 | -0.0112 |
Hs 578T | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 765 | 3121 | 3148 | 0.9914 | 0.9915 |
Hs 578T | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 765 | 3074 | 3101 | 0.9916 | 0.9916 |
Hs 578T | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 765 | 3180 | 3148 | 1.0102 | 1.0100 |
Hs 578T | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 765 | 3026 | 3101 | 0.9761 | 0.9761 |
Hs 578T | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 765 | 2998 | 3148 | 0.9523 | 0.9525 |
Hs 578T | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 765 | 2903 | 3101 | 0.9363 | 0.9359 |
Hs 578T | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 765 | 554 | 3148 | 0.1762 | -0.1458 |
Hs 578T | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 765 | 501 | 3101 | 0.1617 | -0.1891 |
Hs 578T | Withaferin A | 3.33 | uM | LJP5 | 72 | hr | 765 | 605 | 3148 | 0.1922 | -0.1088 |
Hs 578T | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 765 | 593 | 3101 | 0.1914 | -0.1186 |
Hs 578T | Withaferin A | 10 | uM | LJP5 | 72 | hr | 765 | 322 | 3148 | 0.1025 | -0.3466 |
Hs 578T | Withaferin A | 10 | uM | LJP6 | 72 | hr | 765 | 326 | 3101 | 0.1050 | -0.3465 |