LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Seliciclib
0.04
uM
LJP5
 72
hr
 1694 11082 11103 0.9982 0.9986
MCF 10A Seliciclib
0.12
uM
LJP5
 72
hr
 1694 10898 11103 0.9815 0.9859
MCF 10A Seliciclib
0.37
uM
LJP5
 72
hr
 1694 10578 11103 0.9527 0.9644
MCF 10A Seliciclib
1.11
uM
LJP5
 72
hr
 1694 10536 11103 0.9490 0.9614
MCF 10A Seliciclib
3.33
uM
LJP5
 72
hr
 1694 10432 11103 0.9396 0.9544
MCF 10A Seliciclib
10
uM
LJP5
 72
hr
 1694 4986 11103 0.4491 0.4887
MCF 10A AT-7519
0.04
uM
LJP6
 72
hr
 1694 11122 11217 0.9914 0.9935
MCF 10A AT-7519
0.12
uM
LJP6
 72
hr
 1694 10552 11217 0.9407 0.9556
MCF 10A AT-7519
0.37
uM
LJP6
 72
hr
 1694 6457 11217 0.5756 0.6332
MCF 10A AT-7519
1.11
uM
LJP6
 72
hr
 1694 623 11217 0.0556 -0.3072
MCF 10A AT-7519
3.33
uM
LJP6
 72
hr
 1694 314 11217 0.0280 -0.4612
MCF 10A AT-7519
10
uM
LJP6
 72
hr
 1694 253 11217 0.0226 -0.5030
MCF 10A AZD7762
0.04
uM
LJP6
 72
hr
 1694 9157 11217 0.8162 0.8563
MCF 10A AZD7762
0.12
uM
LJP6
 72
hr
 1694 7703 11217 0.6867 0.7424
MCF 10A AZD7762
0.37
uM
LJP6
 72
hr
 1694 6905 11217 0.6155 0.6739
MCF 10A AZD7762
1.11
uM
LJP6
 72
hr
 1694 5059 11217 0.4510 0.4929
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 1694 3091 11217 0.2757 0.2465
MCF 10A AZD7762
10
uM
LJP6
 72
hr
 1694 838 11217 0.0747 -0.2306
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 1694 6286 11217 0.5607 0.6156
MCF 10A AZD8055
0.12
uM
LJP6
 72
hr
 1694 4177 11217 0.3724 0.3920
MCF 10A AZD8055
0.37
uM
LJP6
 72
hr
 1694 3172 11217 0.2828 0.2586
MCF 10A AZD8055
1.11
uM
LJP6
 72
hr
 1694 2755 11217 0.2457 0.1952
MCF 10A AZD8055
3.33
uM
LJP6
 72
hr
 1694 2536 11217 0.2261 0.1591
MCF 10A AZD8055
10
uM
LJP6
 72
hr
 1694 2374 11217 0.2117 0.1313
MCF 10A Sorafenib
0.04
uM
LJP6
 72
hr
 1694 12063 11217 1.0756 1.0540