LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Celastrol
0.37
uM
LJP6
 72
hr
 765 2629 3101 0.8478 0.8430
Hs 578T Celastrol
1.11
uM
LJP6
 72
hr
 765 1725 3101 0.5554 0.4891
Hs 578T Celastrol
3.33
uM
LJP6
 72
hr
 765 618 3101 0.1994 -0.1008
Hs 578T Celastrol
10
uM
LJP6
 72
hr
 765 461 3101 0.1488 -0.2225
Hs 578T SU11274
0.04
uM
LJP5
 72
hr
 765 3235 3148 1.0276 1.0268
Hs 578T SU11274
0.12
uM
LJP5
 72
hr
 765 3171 3148 1.0075 1.0072
Hs 578T SU11274
0.37
uM
LJP5
 72
hr
 765 2978 3148 0.9460 0.9462
Hs 578T SU11274
1.11
uM
LJP5
 72
hr
 765 2770 3148 0.8799 0.8784
Hs 578T SU11274
3.33
uM
LJP5
 72
hr
 765 2548 3148 0.8096 0.8032
Hs 578T SU11274
10
uM
LJP5
 72
hr
 765 886 3148 0.2815 0.0744
Hs 578T Canertinib
0.04
uM
LJP6
 72
hr
 765 3023 3101 0.9747 0.9747
Hs 578T Canertinib
0.12
uM
LJP6
 72
hr
 765 3043 3101 0.9810 0.9811
Hs 578T Canertinib
0.37
uM
LJP6
 72
hr
 765 2951 3101 0.9517 0.9516
Hs 578T Canertinib
1.11
uM
LJP6
 72
hr
 765 2927 3101 0.9437 0.9434
Hs 578T Canertinib
3.33
uM
LJP6
 72
hr
 765 2750 3101 0.8866 0.8843
Hs 578T Canertinib
10
uM
LJP6
 72
hr
 765 240 3101 0.0776 -0.4365
Hs 578T NVP-AEW541
0.04
uM
LJP5
 72
hr
 765 3190 3148 1.0133 1.0129
Hs 578T NVP-AEW541
0.12
uM
LJP5
 72
hr
 765 3194 3148 1.0146 1.0142
Hs 578T NVP-AEW541
0.37
uM
LJP5
 72
hr
 765 3229 3148 1.0259 1.0249
Hs 578T NVP-AEW541
1.11
uM
LJP5
 72
hr
 765 3168 3148 1.0066 1.0062
Hs 578T NVP-AEW541
3.33
uM
LJP5
 72
hr
 765 3119 3148 0.9910 0.9910
Hs 578T NVP-AEW541
10
uM
LJP5
 72
hr
 765 647 3148 0.2055 -0.0789
Hs 578T PHA-665752
0.04
uM
LJP5
 72
hr
 765 3047 3148 0.9678 0.9681
Hs 578T PHA-665752
0.12
uM
LJP5
 72
hr
 765 3165 3148 1.0056 1.0054
Hs 578T PHA-665752
0.37
uM
LJP5
 72
hr
 765 3114 3148 0.9893 0.9895