LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T PHA-665752
1.11
uM
LJP5
 72
hr
 765 3076 3148 0.9773 0.9776
Hs 578T PHA-665752
3.33
uM
LJP5
 72
hr
 765 2945 3148 0.9355 0.9357
Hs 578T PHA-665752
10
uM
LJP5
 72
hr
 765 395 3148 0.1257 -0.2761
Hs 578T PI103
0.04
uM
LJP6
 72
hr
 765 2309 3101 0.7443 0.7276
Hs 578T PI103
0.12
uM
LJP6
 72
hr
 765 1429 3101 0.4608 0.3623
Hs 578T PI103
0.37
uM
LJP6
 72
hr
 765 968 3101 0.3122 0.1237
Hs 578T PI103
1.11
uM
LJP6
 72
hr
 765 768 3101 0.2478 0.0023
Hs 578T PI103
3.33
uM
LJP6
 72
hr
 765 709 3101 0.2286 -0.0371
Hs 578T PI103
10
uM
LJP6
 72
hr
 765 684 3101 0.2207 -0.0537
Hs 578T Dovitinib
0.04
uM
LJP5
 72
hr
 765 2478 3148 0.7873 0.7787
Hs 578T Dovitinib
0.12
uM
LJP5
 72
hr
 765 1856 3148 0.5897 0.5435
Hs 578T Dovitinib
0.37
uM
LJP5
 72
hr
 765 1291 3148 0.4103 0.2926
Hs 578T Dovitinib
1.11
uM
LJP5
 72
hr
 765 1196 3148 0.3800 0.2447
Hs 578T Dovitinib
3.33
uM
LJP5
 72
hr
 765 1140 3148 0.3621 0.2154
Hs 578T Dovitinib
10
uM
LJP5
 72
hr
 765 1157 3148 0.3677 0.2242
Hs 578T GSK 690693
0.04
uM
LJP5
 72
hr
 765 2720 3148 0.8641 0.8615
Hs 578T GSK 690693
0.12
uM
LJP5
 72
hr
 765 2482 3148 0.7886 0.7803
Hs 578T GSK 690693
0.37
uM
LJP5
 72
hr
 765 2221 3148 0.7057 0.6855
Hs 578T GSK 690693
1.11
uM
LJP5
 72
hr
 765 2134 3148 0.6779 0.6528
Hs 578T GSK 690693
3.33
uM
LJP5
 72
hr
 765 2076 3148 0.6596 0.6310
Hs 578T GSK 690693
10
uM
LJP5
 72
hr
 765 2102 3148 0.6679 0.6410
Hs 578T SNS-032
0.04
uM
LJP6
 72
hr
 765 2328 3101 0.7507 0.7353
Hs 578T SNS-032
0.12
uM
LJP6
 72
hr
 765 419 3101 0.1351 -0.2579
Hs 578T SNS-032
0.37
uM
LJP6
 72
hr
 765 422 3101 0.1361 -0.2552
Hs 578T SNS-032
1.11
uM
LJP6
 72
hr
 765 379 3101 0.1225 -0.2933