LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 1694 11824 11217 1.0544 1.0390
MCF 10A Sorafenib
0.37
uM
LJP6
 72
hr
 1694 11440 11217 1.0200 1.0145
MCF 10A Sorafenib
1.11
uM
LJP6
 72
hr
 1694 11015 11217 0.9822 0.9867
MCF 10A Sorafenib
3.33
uM
LJP6
 72
hr
 1694 10506 11217 0.9368 0.9525
MCF 10A Sorafenib
10
uM
LJP6
 72
hr
 1694 6560 11217 0.5849 0.6428
MCF 10A CP466722
0.04
uM
LJP5
 72
hr
 1694 11482 11103 1.0342 1.0249
MCF 10A CP466722
0.12
uM
LJP5
 72
hr
 1694 11356 11103 1.0228 1.0167
MCF 10A CP466722
0.37
uM
LJP5
 72
hr
 1694 11256 11103 1.0138 1.0101
MCF 10A CP466722
1.11
uM
LJP5
 72
hr
 1694 11205 11103 1.0092 1.0068
MCF 10A CP466722
3.33
uM
LJP5
 72
hr
 1694 11006 11103 0.9913 0.9936
MCF 10A CP466722
10
uM
LJP5
 72
hr
 1694 11084 11103 0.9983 0.9987
MCF 10A CP724714
0.04
uM
LJP5
 72
hr
 1694 11221 11103 1.0106 1.0077
MCF 10A CP724714
0.12
uM
LJP5
 72
hr
 1694 10955 11103 0.9867 0.9900
MCF 10A CP724714
0.37
uM
LJP5
 72
hr
 1694 10714 11103 0.9651 0.9739
MCF 10A CP724714
1.11
uM
LJP5
 72
hr
 1694 10697 11103 0.9634 0.9726
MCF 10A CP724714
3.33
uM
LJP5
 72
hr
 1694 10853 11103 0.9775 0.9833
MCF 10A CP724714
10
uM
LJP5
 72
hr
 1694 10255 11103 0.9236 0.9417
MCF 10A Alvocidib
0.04
uM
LJP6
 72
hr
 1694 4715 11217 0.4202 0.4535
MCF 10A Alvocidib
0.12
uM
LJP6
 72
hr
 1694 610 11217 0.0545 -0.3126
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 1694 300 11217 0.0268 -0.4707
MCF 10A Alvocidib
1.11
uM
LJP6
 72
hr
 1694 299 11217 0.0267 -0.4731
MCF 10A Alvocidib
3.33
uM
LJP6
 72
hr
 1694 289 11217 0.0258 -0.4785
MCF 10A Alvocidib
10
uM
LJP6
 72
hr
 1694 336 11217 0.0299 -0.4480
MCF 10A GW843682X
0.04
uM
LJP6
 72
hr
 1694 11015 11217 0.9821 0.9868
MCF 10A GW843682X
0.12
uM
LJP6
 72
hr
 1694 9876 11217 0.8806 0.9089