LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Barasertib
10
uM
LJP5
 72
hr
 1694 2049 11103 0.1846 0.0726
MCF 10A Vemurafenib
0.04
uM
LJP5
 72
hr
 1694 10963 11103 0.9874 0.9906
MCF 10A Vemurafenib
0.12
uM
LJP5
 72
hr
 1694 10857 11103 0.9778 0.9834
MCF 10A Vemurafenib
0.37
uM
LJP5
 72
hr
 1694 10972 11103 0.9882 0.9913
MCF 10A Vemurafenib
1.11
uM
LJP5
 72
hr
 1694 10870 11103 0.9790 0.9844
MCF 10A Vemurafenib
3.33
uM
LJP5
 72
hr
 1694 9108 11103 0.8204 0.8590
MCF 10A Vemurafenib
10
uM
LJP5
 72
hr
 1694 5157 11103 0.4646 0.5069
MCF 10A Enzastaurin
0.04
uM
LJP5
 72
hr
 1694 11228 11103 1.0112 1.0082
MCF 10A Enzastaurin
0.12
uM
LJP5
 72
hr
 1694 11143 11103 1.0035 1.0025
MCF 10A Enzastaurin
0.37
uM
LJP5
 72
hr
 1694 11178 11103 1.0067 1.0049
MCF 10A Enzastaurin
1.11
uM
LJP5
 72
hr
 1694 11564 11103 1.0414 1.0300
MCF 10A Enzastaurin
3.33
uM
LJP5
 72
hr
 1694 11663 11103 1.0504 1.0365
MCF 10A Enzastaurin
10
uM
LJP5
 72
hr
 1694 12028 11103 1.0833 1.0598
MCF 10A Palbociclib
0.04
uM
LJP6
 72
hr
 1694 9116 11217 0.8127 0.8535
MCF 10A Palbociclib
0.12
uM
LJP6
 72
hr
 1694 8038 11217 0.7167 0.7700
MCF 10A Palbociclib
0.37
uM
LJP6
 72
hr
 1694 7285 11217 0.6495 0.7072
MCF 10A Palbociclib
1.11
uM
LJP6
 72
hr
 1694 6292 11217 0.5610 0.6178
MCF 10A Palbociclib
3.33
uM
LJP6
 72
hr
 1694 5616 11217 0.5007 0.5519
MCF 10A Palbociclib
10
uM
LJP6
 72
hr
 1694 4663 11217 0.4157 0.4494
MCF 10A PF562271
0.04
uM
LJP6
 72
hr
 1694 9484 11217 0.8455 0.8806
MCF 10A PF562271
0.12
uM
LJP6
 72
hr
 1694 8613 11217 0.7680 0.8154
MCF 10A PF562271
0.37
uM
LJP6
 72
hr
 1694 6920 11217 0.6170 0.6754
MCF 10A PF562271
1.11
uM
LJP6
 72
hr
 1694 5198 11217 0.4635 0.5085
MCF 10A PF562271
3.33
uM
LJP6
 72
hr
 1694 2166 11217 0.1931 0.0942
MCF 10A PF562271
10
uM
LJP6
 72
hr
 1694 494 11217 0.0440 -0.3639