LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A PHA-793887
0.04
uM
LJP6
 72
hr
 1694 3799 11217 0.3386 0.3440
MCF 10A PHA-793887
0.12
uM
LJP6
 72
hr
 1694 3384 11217 0.3016 0.2885
MCF 10A PHA-793887
0.37
uM
LJP6
 72
hr
 1694 2711 11217 0.2416 0.1874
MCF 10A PHA-793887
1.11
uM
LJP6
 72
hr
 1694 2252 11217 0.2008 0.1098
MCF 10A PHA-793887
3.33
uM
LJP6
 72
hr
 1694 1580 11217 0.1408 -0.0259
MCF 10A PHA-793887
10
uM
LJP6
 72
hr
 1694 558 11217 0.0498 -0.3347
MCF 10A QL-X-138
0.04
uM
LJP6
 72
hr
 1694 12300 11217 1.0965 1.0686
MCF 10A QL-X-138
0.12
uM
LJP6
 72
hr
 1694 12035 11217 1.0729 1.0523
MCF 10A QL-X-138
0.37
uM
LJP6
 72
hr
 1694 11489 11217 1.0240 1.0173
MCF 10A QL-X-138
1.11
uM
LJP6
 72
hr
 1694 11078 11217 0.9875 0.9906
MCF 10A QL-X-138
3.33
uM
LJP6
 72
hr
 1694 8955 11217 0.7981 0.8405
MCF 10A QL-X-138
10
uM
LJP6
 72
hr
 1694 1170 11217 0.1044 -0.1276
MCF 10A QL-XII-47
0.04
uM
LJP6
 72
hr
 1694 11090 11217 0.9886 0.9915
MCF 10A QL-XII-47
0.12
uM
LJP6
 72
hr
 1694 10935 11217 0.9748 0.9814
MCF 10A QL-XII-47
0.37
uM
LJP6
 72
hr
 1694 10729 11217 0.9565 0.9676
MCF 10A QL-XII-47
1.11
uM
LJP6
 72
hr
 1694 10063 11217 0.8972 0.9220
MCF 10A QL-XII-47
3.33
uM
LJP6
 72
hr
 1694 7834 11217 0.6984 0.7517
MCF 10A QL-XII-47
10
uM
LJP6
 72
hr
 1694 806 11217 0.0720 -0.2429
MCF 10A Torin1
0.04
uM
LJP6
 72
hr
 1694 6130 11217 0.5466 0.6002
MCF 10A Torin1
0.12
uM
LJP6
 72
hr
 1694 3778 11217 0.3369 0.3412
MCF 10A Torin1
0.37
uM
LJP6
 72
hr
 1694 2899 11217 0.2585 0.2161
MCF 10A Torin1
1.11
uM
LJP6
 72
hr
 1694 2501 11217 0.2229 0.1504
MCF 10A Torin1
3.33
uM
LJP6
 72
hr
 1694 2554 11217 0.2277 0.1616
MCF 10A Torin1
10
uM
LJP6
 72
hr
 1694 2056 11217 0.1833 0.0719
MCF 10A Torin2
0.04
uM
LJP5
 72
hr
 1694 4382 11103 0.3947 0.4187