LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A XL147
3.33
uM
LJP5
 72
hr
 1694 9760 11103 0.8790 0.9071
MCF 10A XL147
10
uM
LJP5
 72
hr
 1694 5776 11103 0.5203 0.5716
MCF 10A Y39983
0.04
uM
LJP6
 72
hr
 1694 10738 11217 0.9573 0.9681
MCF 10A Y39983
0.12
uM
LJP6
 72
hr
 1694 8937 11217 0.7967 0.8400
MCF 10A Y39983
0.37
uM
LJP6
 72
hr
 1694 9405 11217 0.8385 0.8749
MCF 10A Y39983
1.11
uM
LJP6
 72
hr
 1694 9085 11217 0.8100 0.8513
MCF 10A Y39983
3.33
uM
LJP6
 72
hr
 1694 8452 11217 0.7537 0.8028
MCF 10A Y39983
10
uM
LJP6
 72
hr
 1694 3290 11217 0.2935 0.2745
MCF 10A Nintedanib
0.04
uM
LJP6
 72
hr
 1694 11315 11217 1.0086 1.0060
MCF 10A Nintedanib
0.12
uM
LJP6
 72
hr
 1694 10974 11217 0.9783 0.9839
MCF 10A Nintedanib
0.37
uM
LJP6
 72
hr
 1694 10967 11217 0.9776 0.9833
MCF 10A Nintedanib
1.11
uM
LJP6
 72
hr
 1694 10827 11217 0.9651 0.9740
MCF 10A Nintedanib
3.33
uM
LJP6
 72
hr
 1694 9454 11217 0.8429 0.8785
MCF 10A Nintedanib
10
uM
LJP6
 72
hr
 1694 10976 11217 0.9784 0.9840
MCF 10A Foretinib
0.04
uM
LJP5
 72
hr
 1694 11930 11103 1.0746 1.0537
MCF 10A Foretinib
0.12
uM
LJP5
 72
hr
 1694 11382 11103 1.0252 1.0184
MCF 10A Foretinib
0.37
uM
LJP5
 72
hr
 1694 10225 11103 0.9209 0.9402
MCF 10A Foretinib
1.11
uM
LJP5
 72
hr
 1694 5525 11103 0.4975 0.5452
MCF 10A Foretinib
3.33
uM
LJP5
 72
hr
 1694 2325 11103 0.2094 0.1238
MCF 10A Foretinib
10
uM
LJP5
 72
hr
 1694 1417 11103 0.1276 -0.0643
MCF 10A AZD 5438
0.04
uM
LJP6
 72
hr
 1694 10915 11217 0.9731 0.9801
MCF 10A AZD 5438
0.12
uM
LJP6
 72
hr
 1694 9687 11217 0.8635 0.8951
MCF 10A AZD 5438
0.37
uM
LJP6
 72
hr
 1694 6413 11217 0.5717 0.6292
MCF 10A AZD 5438
1.11
uM
LJP6
 72
hr
 1694 1677 11217 0.1495 -0.0039
MCF 10A AZD 5438
3.33
uM
LJP6
 72
hr
 1694 513 11217 0.0457 -0.3571