LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A AZD 5438
10
uM
LJP6
 72
hr
 1694 574 11217 0.0512 -0.3275
MCF 10A Pelitinib
0.04
uM
LJP5
 72
hr
 1694 8699 11103 0.7835 0.8279
MCF 10A Pelitinib
0.12
uM
LJP5
 72
hr
 1694 5807 11103 0.5230 0.5748
MCF 10A Pelitinib
0.37
uM
LJP5
 72
hr
 1694 2549 11103 0.2296 0.1622
MCF 10A Pelitinib
1.11
uM
LJP5
 72
hr
 1694 2615 11103 0.2356 0.1734
MCF 10A Pelitinib
3.33
uM
LJP5
 72
hr
 1694 2453 11103 0.2209 0.1460
MCF 10A Pelitinib
10
uM
LJP5
 72
hr
 1694 1782 11103 0.1605 0.0171
MCF 10A Luminespib
0.04
uM
LJP5
 72
hr
 1694 1257 11103 0.1132 -0.1044
MCF 10A Luminespib
0.12
uM
LJP5
 72
hr
 1694 1256 11103 0.1132 -0.1045
MCF 10A Luminespib
0.37
uM
LJP5
 72
hr
 1694 1259 11103 0.1134 -0.1037
MCF 10A Luminespib
1.11
uM
LJP5
 72
hr
 1694 1306 11103 0.1176 -0.0919
MCF 10A Luminespib
3.33
uM
LJP5
 72
hr
 1694 1335 11103 0.1203 -0.0841
MCF 10A Luminespib
10
uM
LJP5
 72
hr
 1694 1314 11103 0.1184 -0.0895
MCF 10A AZD8330
0.04
uM
LJP5
 72
hr
 1694 2625 11103 0.2364 0.1750
MCF 10A AZD8330
0.12
uM
LJP5
 72
hr
 1694 2427 11103 0.2185 0.1399
MCF 10A AZD8330
0.37
uM
LJP5
 72
hr
 1694 2519 11103 0.2268 0.1572
MCF 10A AZD8330
1.11
uM
LJP5
 72
hr
 1694 2628 11103 0.2366 0.1749
MCF 10A AZD8330
3.33
uM
LJP5
 72
hr
 1694 2695 11103 0.2428 0.1868
MCF 10A AZD8330
10
uM
LJP5
 72
hr
 1694 2835 11103 0.2554 0.2089
MCF 10A TGX221
0.04
uM
LJP5
 72
hr
 1694 10749 11103 0.9681 0.9762
MCF 10A TGX221
0.12
uM
LJP5
 72
hr
 1694 10876 11103 0.9796 0.9848
MCF 10A TGX221
0.37
uM
LJP5
 72
hr
 1694 10872 11103 0.9792 0.9845
MCF 10A TGX221
1.11
uM
LJP5
 72
hr
 1694 10748 11103 0.9680 0.9762
MCF 10A TGX221
3.33
uM
LJP5
 72
hr
 1694 5070 11103 0.4566 0.4973
MCF 10A TGX221
10
uM
LJP5
 72
hr
 1694 11120 11103 1.0015 1.0010