LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GW843682X
0.37
uM
LJP6
 72
hr
 1694 5668 11217 0.5053 0.5570
MCF 10A GW843682X
1.11
uM
LJP6
 72
hr
 1694 1859 11217 0.1657 0.0341
MCF 10A GW843682X
3.33
uM
LJP6
 72
hr
 1694 970 11217 0.0865 -0.1851
MCF 10A GW843682X
10
uM
LJP6
 72
hr
 1694 715 11217 0.0638 -0.2712
MCF 10A HG-5-113-01
0.04
uM
LJP5
 72
hr
 1694 10424 11103 0.9389 0.9538
MCF 10A HG-5-113-01
0.12
uM
LJP5
 72
hr
 1694 9608 11103 0.8654 0.8957
MCF 10A HG-5-113-01
0.37
uM
LJP5
 72
hr
 1694 8904 11103 0.8019 0.8435
MCF 10A HG-5-113-01
1.11
uM
LJP5
 72
hr
 1694 7639 11103 0.6880 0.7424
MCF 10A HG-5-113-01
3.33
uM
LJP5
 72
hr
 1694 5021 11103 0.4523 0.4926
MCF 10A HG-5-113-01
10
uM
LJP5
 72
hr
 1694 1256 11103 0.1132 -0.1045
MCF 10A HG-5-88-01
0.04
uM
LJP6
 72
hr
 1694 10451 11217 0.9317 0.9488
MCF 10A HG-5-88-01
0.12
uM
LJP6
 72
hr
 1694 9945 11217 0.8866 0.9136
MCF 10A HG-5-88-01
0.37
uM
LJP6
 72
hr
 1694 8518 11217 0.7594 0.8080
MCF 10A HG-5-88-01
1.11
uM
LJP6
 72
hr
 1694 7479 11217 0.6669 0.7238
MCF 10A HG-5-88-01
3.33
uM
LJP6
 72
hr
 1694 6402 11217 0.5708 0.6283
MCF 10A HG-5-88-01
10
uM
LJP6
 72
hr
 1694 5518 11217 0.4919 0.5418
MCF 10A HG-6-64-01
0.04
uM
LJP6
 72
hr
 1694 11289 11217 1.0063 1.0044
MCF 10A HG-6-64-01
0.12
uM
LJP6
 72
hr
 1694 11177 11217 0.9963 0.9970
MCF 10A HG-6-64-01
0.37
uM
LJP6
 72
hr
 1694 11323 11217 1.0095 1.0069
MCF 10A HG-6-64-01
1.11
uM
LJP6
 72
hr
 1694 10460 11217 0.9326 0.9494
MCF 10A HG-6-64-01
3.33
uM
LJP6
 72
hr
 1694 7100 11217 0.6328 0.6893
MCF 10A HG-6-64-01
10
uM
LJP6
 72
hr
 1694 2052 11217 0.1827 0.0528
MCF 10A Neratinib
0.04
uM
LJP5
 72
hr
 1694 5640 11103 0.5080 0.5576
MCF 10A Neratinib
0.12
uM
LJP5
 72
hr
 1694 4371 11103 0.3937 0.4181
MCF 10A Neratinib
0.37
uM
LJP5
 72
hr
 1694 3558 11103 0.3205 0.3144