LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T SB590885
3.33
uM
LJP5
 72
hr
 765 3864 3148 1.2276 1.2113
Hs 578T SB590885
10
uM
LJP5
 72
hr
 765 1092 3148 0.3468 0.1719
Hs 578T Pictilisib
0.04
uM
LJP6
 72
hr
 765 2401 3101 0.7743 0.7620
Hs 578T Pictilisib
0.12
uM
LJP6
 72
hr
 765 2186 3101 0.7050 0.6819
Hs 578T Pictilisib
0.37
uM
LJP6
 72
hr
 765 1791 3101 0.5775 0.5238
Hs 578T Pictilisib
1.11
uM
LJP6
 72
hr
 765 1515 3101 0.4885 0.4024
Hs 578T Pictilisib
3.33
uM
LJP6
 72
hr
 765 1368 3101 0.4410 0.3332
Hs 578T Pictilisib
10
uM
LJP6
 72
hr
 765 1063 3101 0.3428 0.1769
Hs 578T PD184352
0.04
uM
LJP5
 72
hr
 765 2390 3148 0.7592 0.7471
Hs 578T PD184352
0.12
uM
LJP5
 72
hr
 765 2107 3148 0.6695 0.6429
Hs 578T PD184352
0.37
uM
LJP5
 72
hr
 765 1843 3148 0.5856 0.5387
Hs 578T PD184352
1.11
uM
LJP5
 72
hr
 765 1637 3148 0.5201 0.4514
Hs 578T PD184352
3.33
uM
LJP5
 72
hr
 765 1573 3148 0.4996 0.4234
Hs 578T PD184352
10
uM
LJP5
 72
hr
 765 1137 3148 0.3614 0.2145
Hs 578T PLX-4720
0.04
uM
LJP5
 72
hr
 765 3161 3148 1.0041 1.0039
Hs 578T PLX-4720
0.12
uM
LJP5
 72
hr
 765 3499 3148 1.1116 1.1062
Hs 578T PLX-4720
0.37
uM
LJP5
 72
hr
 765 3751 3148 1.1915 1.1790
Hs 578T PLX-4720
1.11
uM
LJP5
 72
hr
 765 3735 3148 1.1865 1.1747
Hs 578T PLX-4720
3.33
uM
LJP5
 72
hr
 765 3306 3148 1.0503 1.0484
Hs 578T PLX-4720
10
uM
LJP5
 72
hr
 765 2248 3148 0.7141 0.6955
Hs 578T Lapatinib
0.04
uM
LJP6
 72
hr
 765 3101 3101 0.9999 0.9999
Hs 578T Lapatinib
0.12
uM
LJP6
 72
hr
 765 3026 3101 0.9758 0.9759
Hs 578T Lapatinib
0.37
uM
LJP6
 72
hr
 765 3048 3101 0.9828 0.9829
Hs 578T Lapatinib
1.11
uM
LJP6
 72
hr
 765 3066 3101 0.9888 0.9888
Hs 578T Lapatinib
3.33
uM
LJP6
 72
hr
 765 3033 3101 0.9780 0.9782