LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Brivanib
1.11
uM
LJP5
 72
hr
 765 2968 3148 0.9429 0.9431
Hs 578T Brivanib
3.33
uM
LJP5
 72
hr
 765 2930 3148 0.9309 0.9311
Hs 578T Brivanib
10
uM
LJP5
 72
hr
 765 2616 3148 0.8312 0.8267
Hs 578T CHIR-99021
0.04
uM
LJP6
 72
hr
 765 3054 3101 0.9849 0.9850
Hs 578T CHIR-99021
0.12
uM
LJP6
 72
hr
 765 2981 3101 0.9616 0.9615
Hs 578T CHIR-99021
0.37
uM
LJP6
 72
hr
 765 2946 3101 0.9502 0.9500
Hs 578T CHIR-99021
1.11
uM
LJP6
 72
hr
 765 2680 3101 0.8647 0.8607
Hs 578T CHIR-99021
3.33
uM
LJP6
 72
hr
 765 2756 3101 0.8890 0.8868
Hs 578T CHIR-99021
10
uM
LJP6
 72
hr
 765 1478 3101 0.4766 0.3850
Hs 578T Linifanib
0.04
uM
LJP6
 72
hr
 765 3104 3101 1.0008 1.0007
Hs 578T Linifanib
0.12
uM
LJP6
 72
hr
 765 3054 3101 0.9847 0.9846
Hs 578T Linifanib
0.37
uM
LJP6
 72
hr
 765 3057 3101 0.9857 0.9858
Hs 578T Linifanib
1.11
uM
LJP6
 72
hr
 765 2959 3101 0.9539 0.9537
Hs 578T Linifanib
3.33
uM
LJP6
 72
hr
 765 2958 3101 0.9536 0.9533
Hs 578T Linifanib
10
uM
LJP6
 72
hr
 765 2587 3101 0.8339 0.8277
Hs 578T PIK-93
0.04
uM
LJP5
 72
hr
 765 3167 3148 1.0060 1.0058
Hs 578T PIK-93
0.12
uM
LJP5
 72
hr
 765 3184 3148 1.0115 1.0112
Hs 578T PIK-93
0.37
uM
LJP5
 72
hr
 765 3122 3148 0.9918 0.9918
Hs 578T PIK-93
1.11
uM
LJP5
 72
hr
 765 2970 3148 0.9436 0.9438
Hs 578T PIK-93
3.33
uM
LJP5
 72
hr
 765 1521 3148 0.4831 0.3991
Hs 578T PIK-93
10
uM
LJP5
 72
hr
 765 685 3148 0.2176 -0.0537
Hs 578T Dactolisib
0.04
uM
LJP5
 72
hr
 765 1114 3148 0.3540 0.2023
Hs 578T Dactolisib
0.12
uM
LJP5
 72
hr
 765 998 3148 0.3171 0.1390
Hs 578T Dactolisib
0.37
uM
LJP5
 72
hr
 765 839 3148 0.2667 0.0464
Hs 578T Dactolisib
1.11
uM
LJP5
 72
hr
 765 798 3148 0.2537 0.0213