LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
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Hs 578T | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 765 | 1144 | 3148 | 0.3635 | 0.2177 |
Hs 578T | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 765 | 1101 | 3101 | 0.3549 | 0.1970 |
Hs 578T | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 765 | 877 | 3148 | 0.2786 | 0.0688 |
Hs 578T | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 765 | 831 | 3101 | 0.2681 | 0.0414 |
Hs 578T | PD0325901 | 10 | uM | LJP5 | 72 | hr | 765 | 643 | 3148 | 0.2045 | -0.0817 |
Hs 578T | PD0325901 | 10 | uM | LJP6 | 72 | hr | 765 | 690 | 3101 | 0.2231 | -0.0538 |
Hs 578T | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 765 | 2541 | 3148 | 0.8071 | 0.8002 |
Hs 578T | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 765 | 2604 | 3101 | 0.8401 | 0.8340 |
Hs 578T | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 765 | 838 | 3148 | 0.2662 | 0.0452 |
Hs 578T | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 765 | 963 | 3101 | 0.3110 | 0.1176 |
Hs 578T | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 765 | 933 | 3148 | 0.2965 | 0.1013 |
Hs 578T | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 765 | 943 | 3101 | 0.3040 | 0.1084 |
Hs 578T | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 765 | 963 | 3148 | 0.3061 | 0.1194 |
Hs 578T | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 765 | 890 | 3101 | 0.2871 | 0.0771 |
Hs 578T | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 765 | 603 | 3148 | 0.1915 | -0.1109 |
Hs 578T | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 765 | 578 | 3101 | 0.1866 | -0.1308 |
Hs 578T | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 765 | 344 | 3148 | 0.1095 | -0.3253 |
Hs 578T | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 765 | 410 | 3101 | 0.1327 | -0.2725 |
Hs 578T | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 765 | 3131 | 3148 | 0.9947 | 0.9948 |
Hs 578T | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 765 | 3058 | 3148 | 0.9716 | 0.9719 |
Hs 578T | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 765 | 2958 | 3148 | 0.9398 | 0.9399 |
Hs 578T | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 765 | 2705 | 3148 | 0.8594 | 0.8567 |
Hs 578T | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 765 | 2090 | 3148 | 0.6639 | 0.6362 |
Hs 578T | YM 201636 | 10 | uM | LJP5 | 72 | hr | 765 | 955 | 3148 | 0.3035 | 0.1126 |
Hs 578T | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 765 | 3150 | 3148 | 1.0005 | 1.0002 |