LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Dovitinib
0.12
uM
LJP5
72
hr
1694 9580 11103 0.8627 0.8938
MCF 10A Dovitinib
0.37
uM
LJP5
72
hr
1694 7094 11103 0.6390 0.6953
MCF 10A Dovitinib
1.11
uM
LJP5
72
hr
1694 5375 11103 0.4842 0.5302
MCF 10A Dovitinib
3.33
uM
LJP5
72
hr
1694 2858 11103 0.2574 0.2126
MCF 10A Dovitinib
10
uM
LJP5
72
hr
1694 1920 11103 0.1730 0.0472
MCF 10A GSK 690693
0.04
uM
LJP5
72
hr
1694 11282 11103 1.0161 1.0118
MCF 10A GSK 690693
0.12
uM
LJP5
72
hr
1694 11154 11103 1.0046 1.0033
MCF 10A GSK 690693
0.37
uM
LJP5
72
hr
1694 10752 11103 0.9684 0.9764
MCF 10A GSK 690693
1.11
uM
LJP5
72
hr
1694 9787 11103 0.8815 0.9091
MCF 10A GSK 690693
3.33
uM
LJP5
72
hr
1694 9870 11103 0.8890 0.9151
MCF 10A GSK 690693
10
uM
LJP5
72
hr
1694 10102 11103 0.9098 0.9314
MCF 10A SNS-032
0.04
uM
LJP6
72
hr
1694 11126 11217 0.9919 0.9940
MCF 10A SNS-032
0.12
uM
LJP6
72
hr
1694 1915 11217 0.1708 0.0460
MCF 10A SNS-032
0.37
uM
LJP6
72
hr
1694 464 11217 0.0414 -0.3793
MCF 10A SNS-032
1.11
uM
LJP6
72
hr
1694 309 11217 0.0276 -0.4641
MCF 10A SNS-032
3.33
uM
LJP6
72
hr
1694 308 11217 0.0275 -0.4650
MCF 10A SNS-032
10
uM
LJP6
72
hr
1694 366 11217 0.0327 -0.4307
MCF 10A Afatinib
0.04
uM
LJP6
72
hr
1694 1726 11217 0.1540 0.0062
MCF 10A Afatinib
0.12
uM
LJP6
72
hr
1694 1655 11217 0.1476 -0.0089
MCF 10A Afatinib
0.37
uM
LJP6
72
hr
1694 1703 11217 0.1519 0.0003
MCF 10A Afatinib
1.11
uM
LJP6
72
hr
1694 1789 11217 0.1596 0.0177
MCF 10A Afatinib
3.33
uM
LJP6
72
hr
1694 1868 11217 0.1666 0.0363
MCF 10A Afatinib
10
uM
LJP6
72
hr
1694 1764 11217 0.1573 0.0144
MCF 10A GSK1904529A
0.04
uM
LJP6
72
hr
1694 7707 11217 0.6872 0.7429
MCF 10A GSK1904529A
0.12
uM
LJP6
72
hr
1694 7248 11217 0.6462 0.7039