LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Canertinib
10
uM
LJP6
 72
hr
 1694 115 11217 0.0103 -0.6274
MCF 10A Withaferin A
10
uM
LJP6
 72
hr
 1694 241 11217 0.0215 -0.5109
MCF 10A AT-7519
10
uM
LJP6
 72
hr
 1694 253 11217 0.0226 -0.5030
MCF 10A CGP60474
3.33
uM
LJP6
 72
hr
 1694 279 11217 0.0249 -0.4874
MCF 10A Alvocidib
3.33
uM
LJP6
 72
hr
 1694 289 11217 0.0258 -0.4785
MCF 10A LDN-193189
10
uM
LJP5
 72
hr
 1694 294 11103 0.0265 -0.4798
MCF 10A Alvocidib
1.11
uM
LJP6
 72
hr
 1694 299 11217 0.0267 -0.4731
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 1694 300 11217 0.0268 -0.4707
MCF 10A Withaferin A
10
uM
LJP5
 72
hr
 1694 297 11103 0.0268 -0.4737
MCF 10A CGP60474
0.12
uM
LJP6
 72
hr
 1694 306 11217 0.0273 -0.4672
MCF 10A SNS-032
3.33
uM
LJP6
 72
hr
 1694 308 11217 0.0275 -0.4650
MCF 10A SNS-032
1.11
uM
LJP6
 72
hr
 1694 309 11217 0.0276 -0.4641
MCF 10A AT-7519
3.33
uM
LJP6
 72
hr
 1694 314 11217 0.0280 -0.4612
MCF 10A Alvocidib
10
uM
LJP6
 72
hr
 1694 336 11217 0.0299 -0.4480
MCF 10A CGP60474
1.11
uM
LJP6
 72
hr
 1694 364 11217 0.0325 -0.4333
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 1694 364 11217 0.0325 -0.4327
MCF 10A SNS-032
10
uM
LJP6
 72
hr
 1694 366 11217 0.0327 -0.4307
MCF 10A WZ3105
10
uM
LJP5
 72
hr
 1694 371 11103 0.0334 -0.4289
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 1694 387 11217 0.0345 -0.4189
MCF 10A WZ3105
3.33
uM
LJP5
 72
hr
 1694 386 11103 0.0348 -0.4207
MCF 10A Celastrol
3.33
uM
LJP6
 72
hr
 1694 403 11217 0.0359 -0.4144
MCF 10A Withaferin A
3.33
uM
LJP6
 72
hr
 1694 405 11217 0.0361 -0.4082
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 1694 405 11103 0.0365 -0.4103
MCF 10A CGP60474
1.11
uM
LJP5
 72
hr
 1694 408 11103 0.0368 -0.4086
MCF 10A WZ3105
1.11
uM
LJP5
 72
hr
 1694 426 11103 0.0384 -0.3990
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