LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Imatinib
0.04
uM
LJP6
72
hr
1389 5983 5445 1.1007 1.1009
MCF7 Crizotinib
0.04
uM
LJP5
72
hr
1389 4267 5905 0.7211 0.7069
MCF7 JW-7-24-1
0.04
uM
LJP6
72
hr
1389 3786 5445 0.6951 0.6611
MCF7 Tozasertib
0.04
uM
LJP5
72
hr
1389 1560 5905 0.2644 0.0573
MCF7 CGP60474
0.04
uM
LJP6
72
hr
1389 727 5445 0.1339 -0.2802
MCF7 PD173074
0.04
uM
LJP6
72
hr
1389 6234 5445 1.1449 1.1423
MCF7 HG-6-64-01
0.04
uM
LJP6
72
hr
1389 6450 5445 1.1889 1.1853
MCF7 Neratinib
0.04
uM
LJP5
72
hr
1389 3737 5905 0.6332 0.6068
MCF7 HG-5-113-01
0.04
uM
LJP5
72
hr
1389 5118 5905 0.8669 0.8678
MCF7 Dasatinib
0.04
uM
LJP6
72
hr
1389 1513 5445 0.2774 0.0419
MCF7 NVP-TAE684
0.04
uM
LJP6
72
hr
1389 4311 5445 0.7910 0.7744
MCF7 CGP60474
0.04
uM
LJP5
72
hr
1389 5969 5905 1.0110 1.0106
MCF7 AT-7519
0.04
uM
LJP6
72
hr
1389 5420 5445 0.9987 0.9994
MCF7 HG-5-88-01
0.04
uM
LJP6
72
hr
1389 3675 5445 0.6770 0.6408
MCF7 Seliciclib
0.04
uM
LJP5
72
hr
1389 5996 5905 1.0155 1.0149
MCF7 AZD7762
0.04
uM
LJP6
72
hr
1389 1987 5445 0.3659 0.2000
MCF7 GW843682X
0.04
uM
LJP6
72
hr
1389 4561 5445 0.8379 0.8267
MCF7 AZD8055
0.04
uM
LJP6
72
hr
1389 1577 5445 0.2898 0.0624
MCF7 Sorafenib
0.04
uM
LJP6
72
hr
1389 5186 5445 0.9513 0.9475
MCF7 CP724714
0.04
uM
LJP5
72
hr
1389 5239 5905 0.8877 0.8892
MCF7 Dasatinib
0.04
uM
LJP5
72
hr
1389 3839 5905 0.6494 0.6252
MCF7 CP466722
0.04
uM
LJP5
72
hr
1389 6297 5905 1.0662 1.0623
MCF7 Alvocidib
0.04
uM
LJP6
72
hr
1389 1631 5445 0.2990 0.0802
MCF7 KIN001-043
0.04
uM
LJP6
72
hr
1389 5537 5445 1.0171 1.0169
MCF7 BMS345541
0.04
uM
LJP6
72
hr
1389 5438 5445 1.0020 1.0029
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