LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Canertinib
10
uM
LJP6
72
hr
1694 115 11217 0.0103 -0.6274
Hs 578T Mitoxantrone
10
uM
LJP5
72
hr
765 172 3148 0.0546 -0.5188
Hs 578T HG-6-64-01
10
uM
LJP6
72
hr
765 174 3101 0.0564 -0.5216
Hs 578T Mitoxantrone
3.33
uM
LJP5
72
hr
765 189 3148 0.0601 -0.4956
Hs 578T Mitoxantrone
10
uM
LJP6
72
hr
765 208 3101 0.0672 -0.4763
Hs 578T Mitoxantrone
3.33
uM
LJP6
72
hr
765 212 3101 0.0687 -0.4709
Hs 578T CGP60474
10
uM
LJP6
72
hr
765 218 3101 0.0704 -0.4644
Hs 578T WH-4-025
10
uM
LJP5
72
hr
765 226 3148 0.0718 -0.4499
Hs 578T LDN-193189
10
uM
LJP5
72
hr
765 230 3148 0.0733 -0.4457
BT-20 A443654
10
uM
LJP6
72
hr
1334 232 3925 0.0593 -0.6746
Hs 578T Canertinib
10
uM
LJP6
72
hr
765 240 3101 0.0776 -0.4365
MCF 10A Withaferin A
10
uM
LJP6
72
hr
1694 241 11217 0.0215 -0.5109
MCF 10A AT-7519
10
uM
LJP6
72
hr
1694 253 11217 0.0226 -0.5030
Hs 578T AT-7519
10
uM
LJP6
72
hr
765 266 3101 0.0862 -0.4158
Hs 578T A443654
10
uM
LJP6
72
hr
765 269 3101 0.0869 -0.4047
BT-20 CGP60474
10
uM
LJP6
72
hr
1334 278 3925 0.0711 -0.6374
MCF 10A CGP60474
3.33
uM
LJP6
72
hr
1694 279 11217 0.0249 -0.4874
BT-20 AT-7519
10
uM
LJP6
72
hr
1334 285 3925 0.0728 -0.6302
MCF 10A Alvocidib
3.33
uM
LJP6
72
hr
1694 289 11217 0.0258 -0.4785
Hs 578T CGP60474
3.33
uM
LJP6
72
hr
765 292 3101 0.0943 -0.3810
MCF 10A LDN-193189
10
uM
LJP5
72
hr
1694 294 11103 0.0265 -0.4798
SK-BR-3 Mitoxantrone
10
uM
LJP6
72
hr
2543 295 5418 0.0546 -0.8617
BT-20 CGP60474
3.33
uM
LJP6
72
hr
1334 295 3925 0.0753 -0.6212
MCF7 Mitoxantrone
10
uM
LJP5
72
hr
1389 296 5905 0.0502 -0.5229
MCF 10A Withaferin A
10
uM
LJP5
72
hr
1694 297 11103 0.0268 -0.4737
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