LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CP724714 | 10 | uM | LJP5 | 72 | hr | 1389 | 3532 | 5905 | 0.5978 | 0.5625 |
| MCF7 | HG-5-113-01 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 1646 | 5905 | 0.2786 | 0.0840 |
| MCF7 | CP466722 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 5916 | 5905 | 1.0023 | 1.0024 |
| MCF7 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 5059 | 5905 | 0.8573 | 0.8579 |
| MCF7 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 4556 | 5905 | 0.7718 | 0.7667 |
| MCF7 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 2373 | 5905 | 0.4013 | 0.2906 |
| MCF7 | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 6357 | 5905 | 1.0767 | 1.0722 |
| MCF7 | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5956 | 5905 | 1.0090 | 1.0087 |
| MCF7 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 5239 | 5905 | 0.8877 | 0.8892 |
| MCF7 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 4672 | 5905 | 0.7922 | 0.7888 |
| MCF7 | HG-5-113-01 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 5118 | 5905 | 0.8669 | 0.8678 |
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 72 | hr | 1389 | 5996 | 5905 | 1.0155 | 1.0149 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5718 | 5905 | 0.9670 | 0.9662 |
| MCF7 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 3820 | 5905 | 0.6458 | 0.6201 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5276 | 5905 | 0.8927 | 0.8934 |
| MCF7 | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 6297 | 5905 | 1.0662 | 1.0623 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5970 | 5905 | 1.0109 | 1.0104 |
| MCF7 | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5956 | 5905 | 1.0082 | 1.0075 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 4844 | 5905 | 0.8197 | 0.8176 |
| MCF7 | CP466722 | 10 | uM | LJP5 | 72 | hr | 1389 | 5776 | 5905 | 0.9766 | 0.9750 |
| MCF7 | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 4654 | 5905 | 0.7877 | 0.7836 |
| MCF7 | CP724714 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 4622 | 5905 | 0.7829 | 0.7787 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 72 | hr | 1389 | 1278 | 5905 | 0.2160 | -0.0411 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 72 | hr | 1389 | 3737 | 5905 | 0.6332 | 0.6068 |
| MCF7 | HG-5-113-01 | 10 | uM | LJP5 | 72 | hr | 1389 | 990 | 5905 | 0.1674 | -0.1512 |