LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GSK1059615 | 10 | uM | LJP5 | 72 | hr | 2543 | 937 | 5752 | 0.1629 | -0.5732 |
| SK-BR-3 | GSK1059615 | 10 | uM | LJP6 | 72 | hr | 2543 | 1016 | 5418 | 0.1876 | -0.5690 |
| SK-BR-3 | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 4882 | 5752 | 0.8488 | 0.7397 |
| SK-BR-3 | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4962 | 5752 | 0.8626 | 0.7638 |
| SK-BR-3 | Brivanib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4890 | 5752 | 0.8501 | 0.7421 |
| SK-BR-3 | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5216 | 5752 | 0.9068 | 0.8401 |
| SK-BR-3 | Brivanib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 5182 | 5752 | 0.9009 | 0.8295 |
| SK-BR-3 | Brivanib | 10 | uM | LJP5 | 72 | hr | 2543 | 5029 | 5752 | 0.8743 | 0.7841 |
| SK-BR-3 | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4451 | 5418 | 0.8210 | 0.6677 |
| SK-BR-3 | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4297 | 5418 | 0.7921 | 0.6126 |
| SK-BR-3 | CHIR-99021 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4528 | 5418 | 0.8345 | 0.6910 |
| SK-BR-3 | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4353 | 5418 | 0.8014 | 0.6273 |
| SK-BR-3 | CHIR-99021 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 4405 | 5418 | 0.8112 | 0.6460 |
| SK-BR-3 | CHIR-99021 | 10 | uM | LJP6 | 72 | hr | 2543 | 3443 | 5418 | 0.6341 | 0.3143 |
| SK-BR-3 | Linifanib | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5610 | 5418 | 1.0356 | 1.0654 |
| SK-BR-3 | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5556 | 5418 | 1.0256 | 1.0470 |
| SK-BR-3 | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5619 | 5418 | 1.0371 | 1.0678 |
| SK-BR-3 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 5508 | 5418 | 1.0171 | 1.0324 |
| SK-BR-3 | Linifanib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 5453 | 5418 | 1.0067 | 1.0127 |
| SK-BR-3 | Linifanib | 10 | uM | LJP6 | 72 | hr | 2543 | 3086 | 5418 | 0.5702 | 0.1948 |
| SK-BR-3 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 6046 | 5752 | 1.0512 | 1.0866 |
| SK-BR-3 | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 6126 | 5752 | 1.0651 | 1.1102 |
| SK-BR-3 | PIK-93 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 6002 | 5752 | 1.0435 | 1.0736 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5700 | 5752 | 0.9911 | 0.9848 |
| SK-BR-3 | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 4410 | 5752 | 0.7667 | 0.5960 |