LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2289 | 5752 | 0.3980 | -0.0855 |
| SK-BR-3 | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2211 | 5752 | 0.3844 | -0.1121 |
| SK-BR-3 | Luminespib | 10 | uM | LJP5 | 72 | hr | 2543 | 2194 | 5752 | 0.3814 | -0.1181 |
| SK-BR-3 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 3814 | 5752 | 0.6632 | 0.4104 |
| SK-BR-3 | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4441 | 5752 | 0.7721 | 0.6053 |
| SK-BR-3 | AZD8330 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4742 | 5752 | 0.8243 | 0.6972 |
| SK-BR-3 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 4838 | 5752 | 0.8411 | 0.7263 |
| SK-BR-3 | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 4947 | 5752 | 0.8601 | 0.7597 |
| SK-BR-3 | AZD8330 | 10 | uM | LJP5 | 72 | hr | 2543 | 4994 | 5752 | 0.8682 | 0.7737 |
| SK-BR-3 | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 4487 | 5752 | 0.7800 | 0.6189 |
| SK-BR-3 | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5018 | 5752 | 0.8725 | 0.7811 |
| SK-BR-3 | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5423 | 5752 | 0.9427 | 0.9020 |
| SK-BR-3 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5742 | 5752 | 0.9982 | 0.9970 |
| SK-BR-3 | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 5576 | 5752 | 0.9694 | 0.9477 |
| SK-BR-3 | TGX221 | 10 | uM | LJP5 | 72 | hr | 2543 | 5492 | 5752 | 0.9548 | 0.9226 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5906 | 5752 | 1.0269 | 1.0456 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5115 | 5418 | 0.9446 | 0.8991 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5599 | 5752 | 0.9733 | 0.9546 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4327 | 5418 | 0.7987 | 0.6271 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4854 | 5752 | 0.8439 | 0.7314 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 3471 | 5418 | 0.6409 | 0.3300 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2580 | 5752 | 0.4486 | 0.0122 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2143 | 5418 | 0.3956 | -0.1458 |
| SK-BR-3 | GSK1059615 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1167 | 5752 | 0.2030 | -0.4844 |
| SK-BR-3 | GSK1059615 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1462 | 5418 | 0.2697 | -0.3988 |