LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | WZ-4-145 | 10 | uM | LJP6 | 72 | hr | 2543 | 1089 | 5418 | 0.2011 | -0.5408 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 1222 | 5752 | 0.2125 | -0.4638 |
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 1188 | 5752 | 0.2067 | -0.4763 |
| SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1190 | 5752 | 0.2070 | -0.4756 |
| SK-BR-3 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1190 | 5752 | 0.2070 | -0.4759 |
| SK-BR-3 | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1303 | 5752 | 0.2266 | -0.4336 |
| SK-BR-3 | WZ3105 | 10 | uM | LJP5 | 72 | hr | 2543 | 1308 | 5752 | 0.2274 | -0.4320 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4144 | 5418 | 0.7627 | 0.5547 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4140 | 5418 | 0.7618 | 0.5527 |
| SK-BR-3 | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4028 | 5418 | 0.7424 | 0.5192 |
| SK-BR-3 | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 3587 | 5418 | 0.6607 | 0.3644 |
| SK-BR-3 | XMD11-50 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 3048 | 5418 | 0.5611 | 0.1746 |
| SK-BR-3 | XMD11-50 | 10 | uM | LJP6 | 72 | hr | 2543 | 2193 | 5418 | 0.4034 | -0.1318 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4045 | 5418 | 0.7472 | 0.5317 |
| SK-BR-3 | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4685 | 5418 | 0.8646 | 0.7498 |
| SK-BR-3 | XMD11-85h | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4635 | 5418 | 0.8556 | 0.7331 |
| SK-BR-3 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4492 | 5418 | 0.8294 | 0.6851 |
| SK-BR-3 | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 2543 | 4600 | 5418 | 0.8484 | 0.7184 |
| SK-BR-3 | XMD11-85h | 10 | uM | LJP6 | 72 | hr | 2543 | 3696 | 5418 | 0.6813 | 0.4046 |
| SK-BR-3 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 4035 | 5752 | 0.7015 | 0.4800 |
| SK-BR-3 | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2098 | 5752 | 0.3647 | -0.1510 |
| SK-BR-3 | XMD16-144 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2278 | 5752 | 0.3961 | -0.0891 |
| SK-BR-3 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2158 | 5752 | 0.3753 | -0.1301 |
| SK-BR-3 | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2262 | 5752 | 0.3933 | -0.0948 |
| SK-BR-3 | XMD16-144 | 10 | uM | LJP5 | 72 | hr | 2543 | 1406 | 5752 | 0.2444 | -0.3956 |