LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2425 | 5418 | 0.4481 | -0.0421 |
| SK-BR-3 | QL-X-138 | 10 | uM | LJP6 | 72 | hr | 2543 | 1254 | 5418 | 0.2318 | -0.4771 |
| SK-BR-3 | QL-XII-47 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4115 | 5418 | 0.7603 | 0.5566 |
| SK-BR-3 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 3824 | 5418 | 0.7067 | 0.4555 |
| SK-BR-3 | QL-XII-47 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2650 | 5418 | 0.4897 | 0.0391 |
| SK-BR-3 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1965 | 5418 | 0.3627 | -0.2112 |
| SK-BR-3 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1409 | 5418 | 0.2602 | -0.4182 |
| SK-BR-3 | QL-XII-47 | 10 | uM | LJP6 | 72 | hr | 2543 | 1744 | 5418 | 0.3221 | -0.2926 |
| SK-BR-3 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2070 | 5418 | 0.3822 | -0.1724 |
| SK-BR-3 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1952 | 5418 | 0.3602 | -0.2161 |
| SK-BR-3 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1917 | 5418 | 0.3545 | -0.2277 |
| SK-BR-3 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1702 | 5418 | 0.3148 | -0.3075 |
| SK-BR-3 | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1639 | 5418 | 0.3028 | -0.3316 |
| SK-BR-3 | Torin1 | 10 | uM | LJP6 | 72 | hr | 2543 | 1414 | 5418 | 0.2612 | -0.4163 |
| SK-BR-3 | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 1780 | 5752 | 0.3094 | -0.2618 |
| SK-BR-3 | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 1789 | 5752 | 0.3111 | -0.2582 |
| SK-BR-3 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1710 | 5752 | 0.2974 | -0.2861 |
| SK-BR-3 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1616 | 5752 | 0.2810 | -0.3196 |
| SK-BR-3 | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1676 | 5752 | 0.2914 | -0.2985 |
| SK-BR-3 | Torin2 | 10 | uM | LJP5 | 72 | hr | 2543 | 1112 | 5752 | 0.1933 | -0.5048 |
| SK-BR-3 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 3377 | 5418 | 0.6233 | 0.2960 |
| SK-BR-3 | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 3543 | 5418 | 0.6538 | 0.3537 |
| SK-BR-3 | WZ-4-145 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 3449 | 5418 | 0.6366 | 0.3216 |
| SK-BR-3 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2903 | 5418 | 0.5356 | 0.1275 |
| SK-BR-3 | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2737 | 5418 | 0.5053 | 0.0692 |