LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HG-5-88-01 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 3697 | 5418 | 0.6820 | 0.4069 |
| SK-BR-3 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4198 | 5418 | 0.7739 | 0.5790 |
| SK-BR-3 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4274 | 5418 | 0.7886 | 0.6077 |
| SK-BR-3 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4381 | 5418 | 0.8077 | 0.6419 |
| SK-BR-3 | HG-5-88-01 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 4038 | 5418 | 0.7453 | 0.5269 |
| SK-BR-3 | HG-5-88-01 | 10 | uM | LJP6 | 72 | hr | 2543 | 2531 | 5418 | 0.4663 | -0.0079 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 6137 | 5418 | 1.1335 | 1.2457 |
| SK-BR-3 | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5967 | 5418 | 1.1017 | 1.1866 |
| SK-BR-3 | HG-6-64-01 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5352 | 5418 | 0.9886 | 0.9809 |
| SK-BR-3 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4412 | 5418 | 0.8151 | 0.6589 |
| SK-BR-3 | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 3312 | 5418 | 0.6114 | 0.2736 |
| SK-BR-3 | HG-6-64-01 | 10 | uM | LJP6 | 72 | hr | 2543 | 1155 | 5418 | 0.2129 | -0.5157 |
| SK-BR-3 | Neratinib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 1625 | 5752 | 0.2826 | -0.3167 |
| SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 1569 | 5752 | 0.2729 | -0.3365 |
| SK-BR-3 | Neratinib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1519 | 5752 | 0.2641 | -0.3546 |
| SK-BR-3 | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1471 | 5752 | 0.2557 | -0.3720 |
| SK-BR-3 | Neratinib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1397 | 5752 | 0.2429 | -0.3991 |
| SK-BR-3 | Neratinib | 10 | uM | LJP5 | 72 | hr | 2543 | 1363 | 5752 | 0.2370 | -0.4115 |
| SK-BR-3 | JW-7-24-1 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4184 | 5418 | 0.7721 | 0.5770 |
| SK-BR-3 | JW-7-24-1 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4455 | 5418 | 0.8218 | 0.6695 |
| SK-BR-3 | JW-7-24-1 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4126 | 5418 | 0.7613 | 0.5566 |
| SK-BR-3 | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 3714 | 5418 | 0.6851 | 0.4128 |
| SK-BR-3 | JW-7-24-1 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 3181 | 5418 | 0.5871 | 0.2266 |
| SK-BR-3 | JW-7-24-1 | 10 | uM | LJP6 | 72 | hr | 2543 | 1552 | 5418 | 0.2859 | -0.3659 |
| SK-BR-3 | Dasatinib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5795 | 5752 | 1.0074 | 1.0126 |