LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5231 | 5418 | 0.9661 | 0.9391 |
| SK-BR-3 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4995 | 5418 | 0.9225 | 0.8584 |
| SK-BR-3 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 4478 | 5418 | 0.8268 | 0.6799 |
| SK-BR-3 | Nintedanib | 10 | uM | LJP6 | 72 | hr | 2543 | 3807 | 5418 | 0.7025 | 0.4462 |
| SK-BR-3 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5875 | 5752 | 1.0214 | 1.0363 |
| SK-BR-3 | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5279 | 5752 | 0.9178 | 0.8595 |
| SK-BR-3 | Foretinib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2697 | 5752 | 0.4690 | 0.0513 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2136 | 5752 | 0.3713 | -0.1379 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2170 | 5752 | 0.3773 | -0.1262 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 72 | hr | 2543 | 1898 | 5752 | 0.3300 | -0.2201 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5060 | 5418 | 0.9339 | 0.8777 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4292 | 5418 | 0.7922 | 0.6150 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 3259 | 5418 | 0.6019 | 0.2555 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1809 | 5418 | 0.3340 | -0.2689 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1311 | 5418 | 0.2420 | -0.4558 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 72 | hr | 2543 | 733 | 5418 | 0.1352 | -0.6804 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5007 | 5752 | 0.8705 | 0.7778 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4239 | 5752 | 0.7370 | 0.5433 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 1687 | 5752 | 0.2933 | -0.2943 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1697 | 5752 | 0.2950 | -0.2909 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1865 | 5752 | 0.3243 | -0.2316 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 72 | hr | 2543 | 1578 | 5752 | 0.2743 | -0.3334 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 2141 | 5752 | 0.3722 | -0.1364 |
| SK-BR-3 | Luminespib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2191 | 5752 | 0.3809 | -0.1190 |
| SK-BR-3 | Luminespib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2194 | 5752 | 0.3814 | -0.1181 |