LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1684 | 5418 | 0.3110 | -0.3149 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1501 | 5418 | 0.2773 | -0.3835 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1289 | 5418 | 0.2380 | -0.4640 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1036 | 5418 | 0.1914 | -0.5613 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 72 | hr | 2543 | 702 | 5418 | 0.1296 | -0.6926 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5577 | 5752 | 0.9696 | 0.9479 |
| SK-BR-3 | Buparlisib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 4773 | 5752 | 0.8299 | 0.7071 |
| SK-BR-3 | Buparlisib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2940 | 5752 | 0.5110 | 0.1305 |
| SK-BR-3 | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1453 | 5752 | 0.2527 | -0.3786 |
| SK-BR-3 | Buparlisib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1281 | 5752 | 0.2228 | -0.4415 |
| SK-BR-3 | Buparlisib | 10 | uM | LJP5 | 72 | hr | 2543 | 1222 | 5752 | 0.2125 | -0.4633 |
| SK-BR-3 | XL147 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 6164 | 5752 | 1.0717 | 1.1212 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5910 | 5752 | 1.0275 | 1.0465 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5762 | 5752 | 1.0018 | 1.0030 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5954 | 5752 | 1.0350 | 1.0592 |
| SK-BR-3 | XL147 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 6038 | 5752 | 1.0496 | 1.0837 |
| SK-BR-3 | XL147 | 10 | uM | LJP5 | 72 | hr | 2543 | 4152 | 5752 | 0.7218 | 0.5162 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4425 | 5418 | 0.8141 | 0.6489 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4380 | 5418 | 0.8060 | 0.6342 |
| SK-BR-3 | Y39983 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4396 | 5418 | 0.8088 | 0.6392 |
| SK-BR-3 | Y39983 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4049 | 5418 | 0.7454 | 0.5230 |
| SK-BR-3 | Y39983 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 3693 | 5418 | 0.6796 | 0.3992 |
| SK-BR-3 | Y39983 | 10 | uM | LJP6 | 72 | hr | 2543 | 1725 | 5418 | 0.3175 | -0.3023 |
| SK-BR-3 | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5779 | 5418 | 1.0666 | 1.1217 |
| SK-BR-3 | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5471 | 5418 | 1.0098 | 1.0179 |