LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | R406 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4396 | 4935 | 0.8904 | 0.8803 |
| MDA-MB-231 | R406 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 4111 | 4935 | 0.8324 | 0.8133 |
| MDA-MB-231 | R406 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 3261 | 4935 | 0.6607 | 0.6080 |
| MDA-MB-231 | R406 | 10 | uM | LJP6 | 72 | hr | 1311 | 1817 | 4935 | 0.3683 | 0.1850 |
| MDA-MB-231 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 1312 | 4935 | 0.2658 | -0.0007 |
| MDA-MB-231 | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 1278 | 4935 | 0.2591 | -0.0135 |
| MDA-MB-231 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 1219 | 4935 | 0.2470 | -0.0377 |
| MDA-MB-231 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 1276 | 4935 | 0.2585 | -0.0152 |
| MDA-MB-231 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1296 | 4935 | 0.2626 | -0.0073 |
| MDA-MB-231 | BI-2536 | 10 | uM | LJP6 | 72 | hr | 1311 | 1245 | 4935 | 0.2523 | -0.0272 |
| MDA-MB-231 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 3906 | 4935 | 0.7916 | 0.7697 |
| MDA-MB-231 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 3262 | 4935 | 0.6612 | 0.6106 |
| MDA-MB-231 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 1805 | 4935 | 0.3659 | 0.1813 |
| MDA-MB-231 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 1147 | 4935 | 0.2326 | -0.0682 |
| MDA-MB-231 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1131 | 4935 | 0.2292 | -0.0750 |
| MDA-MB-231 | A443654 | 10 | uM | LJP6 | 72 | hr | 1311 | 454 | 4935 | 0.0922 | -0.4257 |
| MDA-MB-231 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1311 | 5029 | 5079 | 0.9902 | 0.9897 |
| MDA-MB-231 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1311 | 5295 | 5079 | 1.0428 | 1.0429 |
| MDA-MB-231 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 4944 | 5079 | 0.9739 | 0.9727 |
| MDA-MB-231 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1311 | 4651 | 5079 | 0.9159 | 0.9120 |
| MDA-MB-231 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 4293 | 5079 | 0.8451 | 0.8346 |
| MDA-MB-231 | SB590885 | 10 | uM | LJP5 | 72 | hr | 1311 | 1242 | 5079 | 0.2446 | -0.0278 |
| MDA-MB-231 | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 1311 | 4066 | 4935 | 0.8237 | 0.8068 |
| MDA-MB-231 | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4253 | 4935 | 0.8617 | 0.8497 |
| MDA-MB-231 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 1311 | 3718 | 4935 | 0.7532 | 0.7241 |