LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A PF477736
10
uM
LJP5
 72
hr
 1694 1333 11103 0.1201 -0.0845
MCF 10A LDN-193189
0.04
uM
LJP5
 72
hr
 1694 11145 11103 1.0038 1.0028
MCF 10A LDN-193189
0.12
uM
LJP5
 72
hr
 1694 10887 11103 0.9805 0.9853
MCF 10A LDN-193189
0.37
uM
LJP5
 72
hr
 1694 10795 11103 0.9722 0.9792
MCF 10A LDN-193189
1.11
uM
LJP5
 72
hr
 1694 10759 11103 0.9690 0.9768
MCF 10A LDN-193189
3.33
uM
LJP5
 72
hr
 1694 10406 11103 0.9372 0.9528
MCF 10A LDN-193189
10
uM
LJP5
 72
hr
 1694 294 11103 0.0265 -0.4798
MCF 10A PF431396
0.04
uM
LJP5
 72
hr
 1694 7335 11103 0.6607 0.7166
MCF 10A PF431396
0.12
uM
LJP5
 72
hr
 1694 5698 11103 0.5132 0.5639
MCF 10A PF431396
0.37
uM
LJP5
 72
hr
 1694 3664 11103 0.3300 0.3289
MCF 10A PF431396
1.11
uM
LJP5
 72
hr
 1694 2245 11103 0.2023 0.1093
MCF 10A PF431396
3.33
uM
LJP5
 72
hr
 1694 1880 11103 0.1694 0.0389
MCF 10A PF431396
10
uM
LJP5
 72
hr
 1694 714 11103 0.0643 -0.2731
MCF 10A Celastrol
0.04
uM
LJP6
 72
hr
 1694 11896 11217 1.0605 1.0436
MCF 10A Celastrol
0.12
uM
LJP6
 72
hr
 1694 12410 11217 1.1065 1.0756
MCF 10A Celastrol
0.37
uM
LJP6
 72
hr
 1694 11629 11217 1.0368 1.0267
MCF 10A Celastrol
1.11
uM
LJP6
 72
hr
 1694 6759 11217 0.6027 0.6563
MCF 10A Celastrol
3.33
uM
LJP6
 72
hr
 1694 403 11217 0.0359 -0.4144
MCF 10A Celastrol
10
uM
LJP6
 72
hr
 1694 804 11217 0.0717 -0.2397
MCF 10A SU11274
0.04
uM
LJP5
 72
hr
 1694 11406 11103 1.0273 1.0200
MCF 10A SU11274
0.12
uM
LJP5
 72
hr
 1694 10937 11103 0.9850 0.9889
MCF 10A SU11274
0.37
uM
LJP5
 72
hr
 1694 10329 11103 0.9303 0.9474
MCF 10A SU11274
1.11
uM
LJP5
 72
hr
 1694 9103 11103 0.8199 0.8587
MCF 10A SU11274
3.33
uM
LJP5
 72
hr
 1694 7486 11103 0.6742 0.7293
MCF 10A SU11274
10
uM
LJP5
 72
hr
 1694 5191 11103 0.4675 0.5110