LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A BI-2536
0.12
uM
LJP6
 72
hr
 1694 1063 11217 0.0948 -0.1578
MCF 10A BI-2536
0.37
uM
LJP6
 72
hr
 1694 1182 11217 0.1053 -0.1244
MCF 10A BI-2536
1.11
uM
LJP6
 72
hr
 1694 1247 11217 0.1112 -0.1064
MCF 10A BI-2536
3.33
uM
LJP6
 72
hr
 1694 1239 11217 0.1105 -0.1093
MCF 10A BI-2536
10
uM
LJP6
 72
hr
 1694 1413 11217 0.1261 -0.0659
MCF 10A A443654
0.04
uM
LJP6
 72
hr
 1694 10311 11217 0.9191 0.9387
MCF 10A A443654
0.12
uM
LJP6
 72
hr
 1694 7992 11217 0.7122 0.7644
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 1694 3893 11217 0.3470 0.3566
MCF 10A A443654
1.11
uM
LJP6
 72
hr
 1694 2348 11217 0.2093 0.1265
MCF 10A A443654
3.33
uM
LJP6
 72
hr
 1694 848 11217 0.0756 -0.2249
MCF 10A A443654
10
uM
LJP6
 72
hr
 1694 538 11217 0.0480 -0.3439
MCF 10A SB590885
0.04
uM
LJP5
 72
hr
 1694 11109 11103 1.0005 1.0003
MCF 10A SB590885
0.12
uM
LJP5
 72
hr
 1694 11072 11103 0.9972 0.9979
MCF 10A SB590885
0.37
uM
LJP5
 72
hr
 1694 11288 11103 1.0166 1.0121
MCF 10A SB590885
1.11
uM
LJP5
 72
hr
 1694 11212 11103 1.0098 1.0070
MCF 10A SB590885
3.33
uM
LJP5
 72
hr
 1694 10851 11103 0.9773 0.9831
MCF 10A SB590885
10
uM
LJP5
 72
hr
 1694 7930 11103 0.7142 0.7664
MCF 10A Pictilisib
0.04
uM
LJP6
 72
hr
 1694 9923 11217 0.8847 0.9120
MCF 10A Pictilisib
0.12
uM
LJP6
 72
hr
 1694 9285 11217 0.8278 0.8660
MCF 10A Pictilisib
0.37
uM
LJP6
 72
hr
 1694 7344 11217 0.6550 0.7121
MCF 10A Pictilisib
1.11
uM
LJP6
 72
hr
 1694 5141 11217 0.4585 0.5021
MCF 10A Pictilisib
3.33
uM
LJP6
 72
hr
 1694 3606 11217 0.3216 0.3189
MCF 10A Pictilisib
10
uM
LJP6
 72
hr
 1694 2457 11217 0.2192 0.1453
MCF 10A PD184352
0.04
uM
LJP5
 72
hr
 1694 6894 11103 0.6209 0.6777
MCF 10A PD184352
0.12
uM
LJP5
 72
hr
 1694 5517 11103 0.4968 0.5447