LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 1694 | 1363 | 11103 | 0.1228 | -0.0773 |
MCF 10A | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 1694 | 1167 | 11217 | 0.1041 | -0.1288 |
MCF 10A | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1694 | 1452 | 11103 | 0.1308 | -0.0555 |
MCF 10A | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1694 | 1213 | 11217 | 0.1081 | -0.1154 |
MCF 10A | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 1694 | 1107 | 11103 | 0.0997 | -0.1459 |
MCF 10A | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 1694 | 1042 | 11217 | 0.0929 | -0.1638 |
MCF 10A | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 1694 | 925 | 11103 | 0.0833 | -0.2033 |
MCF 10A | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 1694 | 819 | 11217 | 0.0729 | -0.2369 |
MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11383 | 11103 | 1.0252 | 1.0184 |
MCF 10A | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11015 | 11103 | 0.9921 | 0.9940 |
MCF 10A | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 10243 | 11103 | 0.9225 | 0.9413 |
MCF 10A | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 8880 | 11103 | 0.7998 | 0.8418 |
MCF 10A | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 8260 | 11103 | 0.7439 | 0.7933 |
MCF 10A | YM 201636 | 10 | uM | LJP5 | 72 | hr | 1694 | 3469 | 11103 | 0.3126 | 0.3020 |
MCF 10A | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11487 | 11103 | 1.0346 | 1.0252 |
MCF 10A | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11268 | 11103 | 1.0149 | 1.0109 |
MCF 10A | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 11511 | 11103 | 1.0368 | 1.0266 |
MCF 10A | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11701 | 11103 | 1.0538 | 1.0389 |
MCF 10A | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 10972 | 11103 | 0.9883 | 0.9912 |
MCF 10A | TWS119 | 10 | uM | LJP5 | 72 | hr | 1694 | 2114 | 11103 | 0.1905 | 0.0841 |
MCF 10A | PF477736 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 10659 | 11103 | 0.9600 | 0.9700 |
MCF 10A | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 1694 | 10046 | 11103 | 0.9048 | 0.9275 |
MCF 10A | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 8873 | 11103 | 0.7992 | 0.8413 |
MCF 10A | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 7219 | 11103 | 0.6502 | 0.7065 |
MCF 10A | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1694 | 4724 | 11103 | 0.4254 | 0.4592 |