LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Nilotinib
1.11
uM
LJP5
 72
hr
 1694 11291 11103 1.0169 1.0124
MCF 10A Nilotinib
3.33
uM
LJP5
 72
hr
 1694 11124 11103 1.0020 1.0014
MCF 10A Nilotinib
10
uM
LJP5
 72
hr
 1694 5985 11103 0.5390 0.5911
MCF 10A JNK-9L
0.04
uM
LJP6
 72
hr
 1694 11450 11217 1.0206 1.0147
MCF 10A JNK-9L
0.12
uM
LJP6
 72
hr
 1694 10724 11217 0.9560 0.9672
MCF 10A JNK-9L
0.37
uM
LJP6
 72
hr
 1694 9206 11217 0.8208 0.8603
MCF 10A JNK-9L
1.11
uM
LJP6
 72
hr
 1694 2873 11217 0.2561 0.2134
MCF 10A JNK-9L
3.33
uM
LJP6
 72
hr
 1694 575 11217 0.0512 -0.3276
MCF 10A JNK-9L
10
uM
LJP6
 72
hr
 1694 1045 11217 0.0932 -0.1624
MCF 10A PD0325901
0.04
uM
LJP5
 72
hr
 1694 3665 11103 0.3301 0.3290
MCF 10A PD0325901
0.04
uM
LJP6
 72
hr
 1694 3467 11217 0.3092 0.3003
MCF 10A PD0325901
0.12
uM
LJP5
 72
hr
 1694 3046 11103 0.2744 0.2413
MCF 10A PD0325901
0.12
uM
LJP6
 72
hr
 1694 3039 11217 0.2709 0.2389
MCF 10A PD0325901
0.37
uM
LJP5
 72
hr
 1694 3235 11103 0.2914 0.2692
MCF 10A PD0325901
0.37
uM
LJP6
 72
hr
 1694 2960 11217 0.2640 0.2269
MCF 10A PD0325901
1.11
uM
LJP5
 72
hr
 1694 3004 11103 0.2706 0.2331
MCF 10A PD0325901
1.11
uM
LJP6
 72
hr
 1694 2609 11217 0.2326 0.1711
MCF 10A PD0325901
3.33
uM
LJP5
 72
hr
 1694 2566 11103 0.2312 0.1650
MCF 10A PD0325901
3.33
uM
LJP6
 72
hr
 1694 2257 11217 0.2012 0.1091
MCF 10A PD0325901
10
uM
LJP5
 72
hr
 1694 2253 11103 0.2030 0.1103
MCF 10A PD0325901
10
uM
LJP6
 72
hr
 1694 1942 11217 0.1731 0.0467
MCF 10A Geldanamycin
0.04
uM
LJP5
 72
hr
 1694 2692 11103 0.2424 0.1856
MCF 10A Geldanamycin
0.04
uM
LJP6
 72
hr
 1694 2367 11217 0.2110 0.1283
MCF 10A Geldanamycin
0.12
uM
LJP5
 72
hr
 1694 1651 11103 0.1488 -0.0095
MCF 10A Geldanamycin
0.12
uM
LJP6
 72
hr
 1694 1293 11217 0.1153 -0.0956