LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A CGP60474
10
uM
LJP6
 72
hr
 1694 439 11217 0.0391 -0.3938
MCF 10A PD173074
0.04
uM
LJP6
 72
hr
 1694 11608 11217 1.0349 1.0253
MCF 10A PD173074
0.12
uM
LJP6
 72
hr
 1694 11343 11217 1.0112 1.0082
MCF 10A PD173074
0.37
uM
LJP6
 72
hr
 1694 11132 11217 0.9925 0.9945
MCF 10A PD173074
1.11
uM
LJP6
 72
hr
 1694 10984 11217 0.9793 0.9847
MCF 10A PD173074
3.33
uM
LJP6
 72
hr
 1694 10831 11217 0.9655 0.9743
MCF 10A PD173074
10
uM
LJP6
 72
hr
 1694 6577 11217 0.5864 0.6444
MCF 10A Crizotinib
0.04
uM
LJP5
 72
hr
 1694 10879 11103 0.9799 0.9851
MCF 10A Crizotinib
0.12
uM
LJP5
 72
hr
 1694 10549 11103 0.9501 0.9626
MCF 10A Crizotinib
0.37
uM
LJP5
 72
hr
 1694 9989 11103 0.8997 0.9236
MCF 10A Crizotinib
1.11
uM
LJP5
 72
hr
 1694 9823 11103 0.8847 0.9116
MCF 10A Crizotinib
3.33
uM
LJP5
 72
hr
 1694 9010 11103 0.8115 0.8518
MCF 10A Crizotinib
10
uM
LJP5
 72
hr
 1694 2103 11103 0.1894 0.0827
MCF 10A BMS345541
0.04
uM
LJP6
 72
hr
 1694 11087 11217 0.9884 0.9914
MCF 10A BMS345541
0.12
uM
LJP6
 72
hr
 1694 10725 11217 0.9562 0.9674
MCF 10A BMS345541
0.37
uM
LJP6
 72
hr
 1694 10565 11217 0.9418 0.9563
MCF 10A BMS345541
1.11
uM
LJP6
 72
hr
 1694 10400 11217 0.9271 0.9451
MCF 10A BMS345541
3.33
uM
LJP6
 72
hr
 1694 10317 11217 0.9197 0.9394
MCF 10A BMS345541
10
uM
LJP6
 72
hr
 1694 9042 11217 0.8060 0.8479
MCF 10A KIN001-043
0.04
uM
LJP6
 72
hr
 1694 11293 11217 1.0069 1.0050
MCF 10A KIN001-043
0.12
uM
LJP6
 72
hr
 1694 11044 11217 0.9847 0.9886
MCF 10A KIN001-043
0.37
uM
LJP6
 72
hr
 1694 10973 11217 0.9784 0.9840
MCF 10A KIN001-043
1.11
uM
LJP6
 72
hr
 1694 10833 11217 0.9659 0.9747
MCF 10A KIN001-043
3.33
uM
LJP6
 72
hr
 1694 9973 11217 0.8893 0.9157
MCF 10A KIN001-043
10
uM
LJP6
 72
hr
 1694 5448 11217 0.4854 0.5324