LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Tozasertib
3.33
uM
LJP5
 72
hr
 1694 1961 11103 0.1766 0.0547
MCF 10A Tozasertib
10
uM
LJP5
 72
hr
 1694 1746 11103 0.1573 0.0109
MCF 10A Imatinib
0.04
uM
LJP6
 72
hr
 1694 11138 11217 0.9929 0.9947
MCF 10A Imatinib
0.12
uM
LJP6
 72
hr
 1694 11251 11217 1.0029 1.0021
MCF 10A Imatinib
0.37
uM
LJP6
 72
hr
 1694 11114 11217 0.9908 0.9930
MCF 10A Imatinib
1.11
uM
LJP6
 72
hr
 1694 11255 11217 1.0033 1.0023
MCF 10A Imatinib
3.33
uM
LJP6
 72
hr
 1694 11454 11217 1.0210 1.0151
MCF 10A Imatinib
10
uM
LJP6
 72
hr
 1694 11340 11217 1.0111 1.0079
MCF 10A NVP-TAE684
0.04
uM
LJP6
 72
hr
 1694 9965 11217 0.8883 0.9149
MCF 10A NVP-TAE684
0.12
uM
LJP6
 72
hr
 1694 9404 11217 0.8384 0.8748
MCF 10A NVP-TAE684
0.37
uM
LJP6
 72
hr
 1694 6930 11217 0.6177 0.6759
MCF 10A NVP-TAE684
1.11
uM
LJP6
 72
hr
 1694 6073 11217 0.5413 0.5963
MCF 10A NVP-TAE684
3.33
uM
LJP6
 72
hr
 1694 4764 11217 0.4247 0.4609
MCF 10A NVP-TAE684
10
uM
LJP6
 72
hr
 1694 2966 11217 0.2644 0.2259
MCF 10A CGP60474
0.04
uM
LJP5
 72
hr
 1694 10131 11103 0.9124 0.9333
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 1694 387 11217 0.0345 -0.4189
MCF 10A CGP60474
0.12
uM
LJP5
 72
hr
 1694 679 11103 0.0612 -0.2884
MCF 10A CGP60474
0.12
uM
LJP6
 72
hr
 1694 306 11217 0.0273 -0.4672
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 1694 405 11103 0.0365 -0.4103
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 1694 364 11217 0.0325 -0.4327
MCF 10A CGP60474
1.11
uM
LJP5
 72
hr
 1694 408 11103 0.0368 -0.4086
MCF 10A CGP60474
1.11
uM
LJP6
 72
hr
 1694 364 11217 0.0325 -0.4333
MCF 10A CGP60474
3.33
uM
LJP5
 72
hr
 1694 466 11103 0.0420 -0.3789
MCF 10A CGP60474
3.33
uM
LJP6
 72
hr
 1694 279 11217 0.0249 -0.4874
MCF 10A CGP60474
10
uM
LJP5
 72
hr
 1694 500 11103 0.0451 -0.3665