LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Neratinib
1.11
uM
LJP5
 72
hr
 1694 3257 11103 0.2935 0.2712
MCF 10A Neratinib
3.33
uM
LJP5
 72
hr
 1694 2674 11103 0.2409 0.1829
MCF 10A Neratinib
10
uM
LJP5
 72
hr
 1694 2463 11103 0.2218 0.1474
MCF 10A JW-7-24-1
0.04
uM
LJP6
 72
hr
 1694 11170 11217 0.9960 0.9969
MCF 10A JW-7-24-1
0.12
uM
LJP6
 72
hr
 1694 11636 11217 1.0373 1.0270
MCF 10A JW-7-24-1
0.37
uM
LJP6
 72
hr
 1694 11550 11217 1.0298 1.0217
MCF 10A JW-7-24-1
1.11
uM
LJP6
 72
hr
 1694 11652 11217 1.0389 1.0281
MCF 10A JW-7-24-1
3.33
uM
LJP6
 72
hr
 1694 11504 11217 1.0258 1.0187
MCF 10A JW-7-24-1
10
uM
LJP6
 72
hr
 1694 3936 11217 0.3510 0.3623
MCF 10A Dasatinib
0.04
uM
LJP5
 72
hr
 1694 8979 11103 0.8088 0.8485
MCF 10A Dasatinib
0.04
uM
LJP6
 72
hr
 1694 6203 11217 0.5530 0.6087
MCF 10A Dasatinib
0.12
uM
LJP5
 72
hr
 1694 6014 11103 0.5418 0.5951
MCF 10A Dasatinib
0.12
uM
LJP6
 72
hr
 1694 3709 11217 0.3307 0.3328
MCF 10A Dasatinib
0.37
uM
LJP5
 72
hr
 1694 3080 11103 0.2774 0.2464
MCF 10A Dasatinib
0.37
uM
LJP6
 72
hr
 1694 2661 11217 0.2373 0.1800
MCF 10A Dasatinib
1.11
uM
LJP5
 72
hr
 1694 2422 11103 0.2181 0.1403
MCF 10A Dasatinib
1.11
uM
LJP6
 72
hr
 1694 2061 11217 0.1837 0.0739
MCF 10A Dasatinib
3.33
uM
LJP5
 72
hr
 1694 1852 11103 0.1669 0.0326
MCF 10A Dasatinib
3.33
uM
LJP6
 72
hr
 1694 1327 11217 0.1183 -0.0876
MCF 10A Dasatinib
10
uM
LJP5
 72
hr
 1694 1251 11103 0.1127 -0.1061
MCF 10A Dasatinib
10
uM
LJP6
 72
hr
 1694 871 11217 0.0776 -0.2227
MCF 10A Tozasertib
0.04
uM
LJP5
 72
hr
 1694 6349 11103 0.5718 0.6273
MCF 10A Tozasertib
0.12
uM
LJP5
 72
hr
 1694 2001 11103 0.1802 0.0632
MCF 10A Tozasertib
0.37
uM
LJP5
 72
hr
 1694 2067 11103 0.1862 0.0760
MCF 10A Tozasertib
1.11
uM
LJP5
 72
hr
 1694 1973 11103 0.1777 0.0578